| Apple II 5.25 disk |  Eamon 160: Monty Python & Holy Grail Hb | 1988 | Segerlind, Nathan |
| Apple II 5.25 disk | Eamon 161: Operation Endgame Hb | 1988 | Ruby, Sam |
| Apple II 5.25 disk | Eamon 162: Eamon 7.0 Demo Adventure Hb | 1988 | Zuchowski, Tom |
| Apple II 5.25 disk | Eamon 163: The Sands of Mars Hb | 1988 | Swartz, Ted |
| Apple II 5.25 disk | Eamon 164: A Real Cliffhanger Hb | 1988 | Swartz, Ted |
| Apple II 5.25 disk | Eamon 165: Animal Farm Hb | 1988 | Ruby, Sam |
| Apple II 5.25 disk | Earl Weaver Baseball Model 1445 | 1988 | Electronic Arts CA, USA 14633 |
| IBM PC 5.25in. disk | Earl Weaver Baseball Model 1449 | 1988 | Electronic Arts CA, USA 14633 |
| IBM PC 3.5in. disk | Earl Weaver Baseball Model 1749 | 1988 | Electronic Arts CA, USA 14633 |
| Sinclair ZX Spectrum cass. | Earthlight Model 011897 | 1988 | Firebird Soft. UK 012439 |
| MSX 2 disk | Ease - Philips Desktop | 1988 | Philips Interactive Media, Inc. |
| Coleco Adam disk | Easy as A,B,C & 1,2,3 | 1988 | Wizard's Lair Soft. |
| Sharp MZ-700 type-in | Easy Drive | 1988 | Dempa Shinbunsha Japan |
| Apple II 5.25 disk | Easy Street | 1988 | Mindplay |
| Commodore Amiga 500 disk | Ebonstar | 1988 | MicroIllusions CA, USA |
| Sinclair ZX Spectrum cass. | Echelon | 1988 | US Gold, Ltd. Birmingham, England 13442 |
| Amstrad CPC cass. | Echelon | 1988 | US Gold, Ltd. Birmingham, England 13442 |
| Sinclair ZX Spectrum+3 disk | Echelon | 1988 | US Gold, Ltd. Birmingham, England 13442 |
| Amstrad CPC 464 disk | Echelon | 1988 | US Gold, Ltd. Birmingham, England 13442 |
| Apple II 5.25 disk | Echelon | 1988 | Access Soft., Inc. |
| Commodore Amiga 500 disk | ECO | 1988 | Ocean Soft., Ltd. 13156 |
| Amstrad CPC cass. | Eddie Edwards Super Ski | 1988 | Microïds |
| Commodore C64 disk | Eddie Edwards Super Ski | 1988 | Microïds |
| IBM PC DOS pack. | EGA Poker | 1988 | Junod, John A. |
| IBM PC DOS pack. | EGA Trek Sw | 1988 | Arcanum Computing |
| IBM PC DOS pack. | EGA-Solitaire | 1988 | Junod, John A. |
| Nintendo Famicom cart. | Eggerland - Meikyuu no Fukkatsu Model HAL-EG | 1988 | HAL Laboratory, Inc. Japan |
| Nintendo Famicom disk | Eggerland - Souzou e no Tabidachi Model HAL-EGS | 1988 | HAL Laboratory, Inc. Japan |
| Videoton TVC disk | Egybeirjam? Különírjam? 1 | 1988 | Novotrade Rt. Hungary |
| Videoton TVC disk | Egybeirjam? Különírjam? 2 | 1988 | Novotrade Rt. Hungary |
| NEC PC-6001 type-in | Eight Direction Search | 1988 | Dempa Shinbunsha Japan |
| Amstrad CPC type-in | Einsiedler Spiel | 1988 | DMV Daten und Medien Verlag Eschwege, Germany |
| Amstrad CPC/ZX Spectrum cass. |  El Cid Model 1SA 0280 | 1988 | Mastertronic, Ltd. UK 012967 |
| Amstrad CPC cass. | El Cid Model 3DR-002 | 1988 | Dro Soft. Madrid, Spain |
| Sinclair ZX Spectrum+3 disk | El Equipo A | 1988 | Zafiro Soft. Div. Spain |
| Sinclair ZX Spectrum cass. | El Equipo A Model 60110647 | 1988 | Zafiro Soft. Div. Spain |
| Amstrad CPC cass. | El Equipo A Model 60130647 | 1988 | Zafiro Soft. Div. Spain |
| Amstrad CPC cass. | El Equipo A Model 60130650 | 1988 | Zafiro Soft. Div. Spain |
| Amstrad CPC 464 disk | El Equipo A Model 61850648 | 1988 | Zafiro Soft. Div. Spain |
| Amstrad CPC 464 disk | El Equipo A Model 61850651 | 1988 | Zafiro Soft. Div. Spain |
