| Sinclair ZX Spectrum cass. |  Downhill Champion | 1988 | Lambourne Games |
| Nintendo NES cart. | Dr. Chaos Model NES-DC-USA | 1988 | FCI Fujisankei Communications International |
| Amstrad CPC type-in | Dr. Dustbin | 1988 | DMV Daten und Medien Verlag Eschwege, Germany |
| Sinclair ZX Spectrum cass. | Dr. Jekyll and Mr. Hyde | 1988 | Essential Myth, The |
| Sinclair ZX Spectrum+3 disk | Dr. Jekyll and Mr. Hyde | 1988 | Zenobi Soft. |
| Arcade Video game |  Dr. Toppel's Adventure | 1988 | Taito Corp. Japan |
| Arcade Video game | Dr. Toppel's Tankentai | 1988 | Taito Corp. Japan |
| Atari 400/800 cass. | Draconus | 1988 | Cognito |
| Commodore C64 cass. | Draconus | 1988 | Zeppelin Games |
| Atari 400/800 disk | Draconus | 1988 | Cognito |
| Sinclair ZX Spectrum cass. | Draconus Model S034 | 1988 | Zeppelin Games |
| NEC PC-8001mkII type-in | Dragon | 1988 | Dempa Shinbunsha Japan |
| Nintendo Famicom cart. | Dragon Ball - Dai Maou Fukkatsu | 1988 | Bandai Co., Ltd. Japan |
| Sharp MZ-80B type-in | Dragon Bustard | 1988 | Dempa Shinbunsha Japan |
| Hitachi MB-6880 (BM-LII) type-in | Dragon Crystal | 1988 | Dempa Shinbunsha Japan |
| Fujitsu FM-7 type-in | Dragon Hunter | 1988 | Dempa Shinbunsha Japan |
| NEC PC-8001 type-in | Dragon Master | 1988 | Dempa Shinbunsha Japan |
| Sinclair ZX Spectrum+3 disk | Dragon Ninja | 1988 | Erbe Soft. Spain |
| Nintendo NES cart. | Dragon Power Model NES-DP-USA | 1988 | Bandai America, Inc. 45557 |
| NEC PC-8801 Series disk | Dragon Princess - Meikyuu no Madoushi | 1988 | Pasoket |
| MSX cart. | Dragon Quest II - Akuryou no Kamigami Model E-G206 P | 1988 | Enix, Ltd. Japan |
| MSX 2 cart. | Dragon Quest II - Akuryou no Kamigami Model E-G207 P | 1988 | Enix, Ltd. Japan |
| Nintendo Famicom cart. | Dragon Quest III - Soshite Densetsu e... Model EFC-D3 | 1988 | Enix, Ltd. Japan |
| NEC PC-9801 Series type-in | Dragon Quest Special | 1988 | Dempa Shinbunsha Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Spirit Model DP-3205006 P | 1988 | Dempa Shinbunsha Japan |
| NEC PC-Engine HuCARD | Dragon Spirit Model NC63003 P | 1988 | NAMCOT Japan |
| Sinclair ZX Spectrum cass. | Dragonia | 1988 | Astros Productions |
| Arcade Video game | Dragonninja | 1988 | Data East Corp. Japan |
| Video Slot Machine | Draw 88 Poker | 1988 | BTE, Inc. |
| Pachinko | Dream | 1988 | Okumura Japan |
| Pachinko | Dream 3 | 1988 | Okumura Japan |
| Pachinko | Dream W | 1988 | Okumura Japan |
| Sinclair ZX Spectrum cass. | Dream Warrior | 1988 | US Gold, Ltd. Birmingham, England 13442 |
| Amstrad CPC cass. | Dream Warrior | 1988 | US Gold, Ltd. Birmingham, England 13442 |
| Amstrad CPC 464 disk | Dream Warrior | 1988 | US Gold, Ltd. Birmingham, England 13442 |
| Commodore C64 cass. | Dream Warrior | 1988 | US Gold, Ltd. Birmingham, England 13442 |
| Amstrad CPC cass. | Dream Warrior Model AM 457 | 1988 | Erbe Soft. Spain |
| Pachinko | Dream X | 1988 | Okumura Japan |
| Apple IIGS disk | Dream Zone | 1988 | Baudville |
| Acorn Electron 3.5in. disk | Dreamtime | 1988 | Heyley Soft. |
