| Amstrad CPC cass. |  Desolator - Halls Of Kyros Model AM 456 | 1988 | Erbe Soft. Spain |
| Commodore Amiga 500 disk | Destroyer | 1988 | Epyx, Inc. Redwood City, CA, USA |
| IGT Player's Edge Plus ROM kit | Deuces Joker Wild Poker Model PP0127 | 1988 | IGT International Game Technologies Reno, NV, USA |
| IGT Player's Edge Plus ROM kit | Deuces Joker Wild Poker Model PP0143 | 1988 | IGT International Game Technologies Reno, NV, USA |
| IGT Player's Edge ROM kit | Deuces Wild Poker Model PK0885 | 1988 | IGT International Game Technologies Reno, NV, USA |
| IGT Player's Edge Plus ROM kit | Deuces Wild Poker Model PP0055 | 1988 | IGT International Game Technologies Reno, NV, USA |
| IGT Player's Edge Plus ROM kit | Deuces Wild Poker Model PP0057 | 1988 | IGT International Game Technologies Reno, NV, USA |
| IGT Player's Edge Plus ROM kit | Deuces Wild Poker Model PP0103 | 1988 | IGT International Game Technologies Reno, NV, USA |
| IGT Player's Edge Plus ROM kit | Deuces Wild Poker Model PP0122 | 1988 | IGT International Game Technologies Reno, NV, USA |
| IGT Player's Edge Plus ROM kit | Deuces Wild Poker Model PP0125 | 1988 | IGT International Game Technologies Reno, NV, USA |
| IGT Player's Edge Plus ROM kit | Deuces Wild Poker Model PP0126 | 1988 | IGT International Game Technologies Reno, NV, USA |
| Arcade Video game |  Devastators Model GX890 | 1988 | Konami Industry Co., Ltd. Japan |
| MSX 2 type-in | Devil Attack | 1988 | Dempa Shinbunsha Japan |
| Commodore C64 disk | Devon Aire in the Hidden Diamond Caper | 1988 | Epyx, Inc. Redwood City, CA, USA |
| Sega SC-3000 type-in | Deworld | 1988 | Dempa Shinbunsha Japan |
| Sega SC-3000 type-in | Deworld II | 1988 | Dempa Shinbunsha Japan |
| Sharp X1 5.25in. disk | Diablo | 1988 | Broderbund Japan |
| NEC PC-8801 Series disk | Diablo | 1988 | Broderbund Japan |
| Commodore Amiga 500 disk | Diablo | 1988 | Diamond Robtek label |
| Atari ST disk | Diablo | 1988 | Diamond Robtek label |
| Sinclair ZX Spectrum cass. | Diablo! | 1988 | Nebula Designs Soft. |
| Amstrad CPC type-in | Diabolo | 1988 | Editions SORACOM France |
| Nintendo Famicom BASIC type-in | Diamond Dust | 1988 | Dempa Shinbunsha Japan |
| Pinball | Diamond Lady Model 711 | 1988 | Premier Technology Co. Bensenville, IL, USA |
| Sinclair ZX Spectrum cass. | Diamond Model URK 903 | 1988 | Destiny Soft. |
| Commodore C64 disk | Didi Dash 1+2 Hb | 1988 | Boulder Didi |
| Amstrad CPC type-in | Die Berlinerin | 1988 | DMV Daten und Medien Verlag Eschwege, Germany |
| Commodore C64 disk | Diego-Dash #10 Hb | 1988 | Lord Diego |
| Commodore C64 disk | Diego-Dash #11 Hb | 1988 | Lord Diego |
| Commodore C64 disk | Diego-Dash #12 Hb | 1988 | Lord Diego |
| Commodore C64 disk | Diego-Dash #13 Hb | 1988 | Lord Diego |
| Commodore C64 disk | Diego-Dash #14 Hb | 1988 | Lord Diego |
| Commodore C64 disk | Diego-Dash #15 Hb | 1988 | Lord Diego |
| Commodore C64 disk | Diego-Dash #16 Hb | 1988 | Lord Diego |
| Commodore C64 disk | Diego-Dash #17 Hb | 1988 | Lord Diego |
| Commodore C64 disk | Diego-Dash Remix Hb | 1988 | Lord Diego |
| VEB Mikroelektronik KC cass. | Digger/3 | 1988 | VEB Mikroelektronik |
| VEB Mikroelektronik KC cass. | Digger/4 | 1988 | VEB Mikroelektronik |
| Sharp MZ-700 type-in | Dipper | 1988 | Dempa Shinbunsha Japan |
| NEC PC-8801 Series disk | Director Monogatari Model P-5075~78 | 1988 | Cross Media Soft Japan |
