| Microsoft XBOX 360 disc |  Resonance of Fate | 2010 | SEGA Corp. |
| Sony PlayStation 3 disc |  Resonance of Fate Model BLES-00789 | 2010 | SEGA Europe Ltd. |
| Sony PlayStation 3 disc | Resonance of Fate Model BLUS-30484 | 2010 | SEGA of America, Inc. San Francisco, CA, USA |
| PC/MS-Windows pack. | Restaurant Empire | 2010 | GOG sp. z o.o. |
| Apple Store pack. | Restaurant Story | 2010 | Unknown |
| PC/MS-Windows pack. | Return to Krondor | 2010 | GOG sp. z o.o. |
| Apple Store pack. | Revenant Rising | 2010 | Unknown |
| Sony PSN: Shodai PS Archives pack. |  Reverthion Model NPJI-????? | 2010 | SEGA Corp. |
| BlackBerry pack. | Revival 2 | 2010 | Unknown |
| GamePark GP2X Caanoo card | Rhythmos | 2010 | GamePark |
| GamePark GP2X Wiz cart. | Rhythmos | 2010 | GamePark |
| Slot Machine | Rhythms of Rio | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
| Slot Machine | Riches of the Heart | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
| Commodore C64 disk | Richi Dash 1 Hb | 2010 | Subotai |
| Commodore C64 disk | Richi Dash 2 - The Voodoo Caves Hb | 2010 | Subotai |
| Apple Store pack. | Ricochet Infinity | 2010 | Unknown |
| Apple Store pack. | Ride or Die | 2010 | Unknown |
| Pachislot | Ring ni Kakero 1 - Ougon no Nippon Jr. Hen | 2010 | Taiyo Co., Ltd. Japan |
| Slot Machine | Ring of Riches Magic Money | 2010 | Bally Tech., Inc. |
| Video Slot Machine | Ring-A-Bell | 2010 | Astra Games, Ltd. Novomatic Group Bridgend, Mid Glamorgan UK |
| PC/MS-Windows CD | Rise of Prussia | 2010 | Paradox Interactive |
| Apple Store pack. | Rise of the Triad - Dark War | 2010 | Unknown |
| Microsoft XBOX 360 disc | Risen | 2010 | Deep Silver, Inc. |
| Apple Store pack. | Risk - The Official Game | 2010 | Unknown |
| Apple Store pack. | Riven - The Sequel to Myst | 2010 | Unknown |
| Slot Machine | Riyauzai | 2010 | AGT Advanced Games Technology Taiwan |
| Arcade Video game | Road Fighters | 2010 | Konami Digital Ent. Co., Ltd. |
| Slot Machine | Roaming Reels Play 50/100 Lines Game Plus | 2010 | Ainsworth Game Technology, Ltd. |
| Slot Machine | Roaring Forties Cool Fire II | 2010 | AGI Austrian Gaming Industries Novomatic Group |
| Slot Machine | Robin Hood and the Golden Arrow G+ Deluxe | 2010 | WMS Gaming, Inc. Chicago, IL, USA |
| Apple Store pack. | Robokill - Titan Prime | 2010 | Unknown |
| Sinclair ZX Spectrum cass. | Robore Hb | 2010 | Mojon Twins, The |
| Apple Store pack. | Robot Story | 2010 | Unknown |
| Apple Store pack. | Robot Unicorn Attack | 2010 | Unknown |
| Apple Store pack. | Robot Unicorn Attack - Christmas Edition | 2010 | Unknown |
| Apple Store pack. | Robot Unicorn Attack - Heavy Metal | 2010 | Unknown |
| Slot Machine | Rock Around the Clock - Party All Night | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
| Slot Machine | Rock Around the Clock - Rhythm 'n' Riches | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
| Slot Machine | Rock Around the Clock - Rock All Day | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
| Slot Machine | Rock Around the Clock - Shakes 'n' Spins | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
