| Video Slot Machine |  Ultimate Nudge | 1981 | Summit Coin |
| Arcade Video game | Ultra Dome | 1981 | Konami Industry Co., Ltd. Japan |
| Redemption mechanical game | Unknow Astro Boy game | 1981 | Unknown Japan |
| Video Slot Machine | Unknown horse gambling game | 1981 | Unknown Japan |
| TRS-80 cass. | Up Periscope | 1981 | Ramware |
| Apple II 5.25 disk | Up'n Down | 1981 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Fruit Machine | Upstairs 'N' Downstairs All Cash ver. | 1981 | Bell-Fruit Mfg. Co., Ltd. B.F.M. UK |
| Mattel Intellivision cart. | USCF Chess Model 3412 | 1981 | Mattel Electronics Mattel, Inc. |
| Mattel Intellivision cart. | Utopia Model 5149 | 1981 | Mattel Electronics Mattel, Inc. |
| Arcade Video game |  Vanguard | 1981 | Centuri, Inc. Hialeah, FL, USA |
| Arcade Video game | Vanguard | 1981 | Zaccaria Bologna, Italy |
| Arcade Video game | Vanguard | 1981 | SNK Corp. Shin Nihon Kikaku Japan |
| Video Slot Machine | Vengt et Un | 1981 | Omega Products Carlsbad, CA, USA |
| Arcade Video game | Venture | 1981 | Exidy, Inc. Sunnyvale, CA, USA |
| Commodore PET cass. | Verbs - Being | 1981 | Microcomputers in Education |
| Commodore VIC-20 cart. | VIC Avenger Model VIC-1901 | 1981 | Commodore, Ltd. |
| Commodore VIC-20 cart. | VIC Super Lander NTSC | 1981 | Commodore, Ltd. |
| Arcade Video game | Video Hustler Model GX343 | 1981 | Konami Industry Co., Ltd. Japan |
| Atari 2600 cart. | Video Life Model CM002 | 1981 | CommaVid, Inc. Aurora, IL, USA |
| Atari 2600 cart. | Video Pinball Model CX2648P | 1981 | Atari, Inc. CA, USA |
| Atari 2600 cart. | Video Pinball Model CX2648 | 1981 | Atari, Inc. CA, USA |
| Rowtron Television Computer System cart. | Video Pinball No. 17 | 1981 | Rowtron |
| Fairchild Channel F cart. | Videocart-24 | 1981 | Zircon |
| Fairchild Channel F cart. | Videocart-25 | 1981 | Zircon |
| Fairchild Channel F cart. | Videocart-26 | 1981 | Zircon |
| Arcade Video game |  Videoman | 1981 | Gottlieb & Co., D. Chicago, IL, USA |
| Pinball | Viper | 1981 | Stern Electronics, Inc. Elk Grove Village, IL, USA |
| Atari 2600 cart. | Vídeo-Flipperama | 1981 | Polyvox Brazil |
| TRS-80 type-in | Volcano | 1981 | SoftSide Publications, Inc. |
| Atari 400/800 type-in | Volcano P | 1981 | SoftSide Publications, Inc. |
| Pinball | Volcano Model 667 | 1981 | Gottlieb & Co., D. Chicago, IL, USA |
| Apple II 5.25 disk | Volcanoes | 1981 | Earthware Computer Services |
| Apple II type-in | Volleyball | 1981 | SoftSide Publications, Inc. |
| Sharp MZ-80K type-in | Volleyball | 1981 | Kohgaku-Sha Co.,Ltd. |
| Texas instrument TI-99/4A cass. | Voodoo Castle Model PHT 6048 | 1981 | Texas Instruments |
| Commodore VIC-20 cart. | Voodoo Castle Model VIC-1918 | 1981 | Commodore, Ltd. |
| Arcade Video game | Voyager | 1981 | Century Electronics, Ltd. England |
| Arcade Video game |  VS Computer Mahjong | 1981 | Nichibutsu Nihon Bussan Co., Ltd. Osaka, Japan |
| Slot Machine | War Eagle | 1981 | Auto-Bell Novelty Co. Chicago, IL, USA |
| Arcade Video game | War of the Bugs or Monsterous Manouvers in a Mushroom Maze | 1981 | Armenia, Ltd. |
