Released exclusively in Japan for the Super Famicom in February 17, 1995. The only game in the series released exclusive for the home market.
The title of the game translates to "Fighter's History - Mizoguchi's Moment of Crisis".
The final boss of the game is Chelnov, who joins Karnov as another character from his own game to appear in the Fighter's History series. Chelnov is the protagonist of Data East's arcade game Atomic Runner Chelnov.
Ray, the main character of the first two games, makes an appearance at the beginning of the Mizoguchi mode, confronting Chelnov.
Matlok, the fighting rocker, appears after the second fight of Mizoguchi mode on difficulty level 3.
Samchay, the muay thai kickboxer, appears after the second fight of Mizoguchi mode on difficulty level 4.
Marstorius, the professional wrestler, appears along with his wife after the second fight of Mizoguchi mode on difficulty level 5.
Jean, the gymnast, appears after the fifth fight of Mizoguchi mode to lend Mizoguchi his private plane.
Ox, the bull from Karate Champ, is seen dragging Mizoguchi at the end of the Mizoguchi mode.
Pony Canyon / Scitron released a limited edition soundtrack album for this game (Fighter's History Dynamite NEO-GEO CD & Mizoguchi Kiki Ippatsu!! - PCCB-00182) on May 19, 1995.