| Texas instrument TI-99/4A cart. |  Robotron: 2084 Model RX8519 | 1983 | Atarisoft Atari, Inc. |
| Texas instrument TI-99/4A cart. | Rotor Raiders | 1983 | Romox, Inc. Campbell, CA, USA |
| Texas instrument TI-99/4A cart. | Ruptus Hb | 2022 | Inufuto |
| Texas instrument TI-99/4A cart. | Saguaro City Model PHM 3052 | 1981 | Texas Instruments |
| Texas instrument TI-99/4A cart. | Salary Planner | 1980 | Foresman & Co., Scott |
| Texas instrument TI-99/4A cart. | Schachmeister Model PHM 3008 | 1979 | Texas Instruments |
| Texas instrument TI-99/4A cart. | Schnoz-ola | 1983 | Funware |
| Texas instrument TI-99/4A cart. | School Mailer | 1981 | Foresman & Co., Scott |
| Texas instrument TI-99/4A cart. | Securities Analysis Model PHM 3012 | 1979 | Texas Instruments |
| Texas instrument TI-99/4A cart. | Sewermania | 1983 | MB Milton Bradley Co. East Longmeadow, MA, USA |
| Texas instrument TI-99/4A cart. | Shamus Model RX8518 | 1983 | Atarisoft Atari, Inc. |
| Texas instrument TI-99/4A cart. | Shanghai | 1983 | Funware |
| Texas instrument TI-99/4A cart. | Simon Says | 1983 | Texas Instruments |
| Texas instrument TI-99/4A cart. | Slymoids Model PHM 3197 | 1983 | Texas Instruments |
| Texas instrument TI-99/4A cart. | Sneggit Model PHM 3145 | 1982 | Texas Instruments |
| Texas instrument TI-99/4A cart. | Soccer Model PHM 3024 | 1980 | Texas Instruments |
| Texas instrument TI-99/4A cart. | Sorgan II | 1988 | DaTaBioTics |
| Texas instrument TI-99/4A cart. | Soundtrack Trolley | 1983 | MB Milton Bradley Co. East Longmeadow, MA, USA |
| Texas instrument TI-99/4A cart. | Space Bandits Model PHM 3149 | 1983 | MB Milton Bradley Co. East Longmeadow, MA, USA |
| Texas instrument TI-99/4A cart. | Space Journey | 1983 | Foresman & Co., Scott |
| Texas instrument TI-99/4A cart. | Space Patrol | 1983 | Sunware |
| Texas instrument TI-99/4A cart. | Springer | 1983 | Tigervision Tiger Electronic Toys, Inc. Orchard Mundelein, IL, USA |
| Texas instrument TI-99/4A cart. | Spy's Demise | 1987 | CSI Design Group |
| Texas instrument TI-99/4A cart. | St. Nick | 1983 | Funware |
| Texas instrument TI-99/4A cart. | Star Gazer I | 1984 | Video Magic |
| Texas instrument TI-99/4A cart. | Star Gazer II | 1984 | Video Magic |
| Texas instrument TI-99/4A cart. | Star Gazer III | 1984 | Video Magic |
| Texas instrument TI-99/4A cart. | Star Maze | 1983 | Foresman & Co., Scott |
| Texas instrument TI-99/4A cart. | Star Runner | 1987 | DaTaBioTics |
| Texas instrument TI-99/4A cart. | Star Trek Model PHM 3225 | 1983 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Texas instrument TI-99/4A cart. | Star Wars | 1984 | Phillips, John |
| Texas instrument TI-99/4A cart. | Statistics Model PHM 3014 | 1979 | Texas Instruments |
| Texas instrument TI-99/4A cart. | Statistik Model PHM 3014 | 1980 | Texas Instruments |
| Texas instrument TI-99/4A cart. | Story Machine Model PHM 3178 | 1983 | Spinnaker Soft. Corp. |
| Texas instrument TI-99/4A cart. | Strike Three! | 1988 | Phillips, John |
| Texas instrument TI-99/4A cart. | Submarine Battle | 1982 | Texas Instruments |
| Texas instrument TI-99/4A cart. | Submarine Commander | 1983 | Thorn EMI Video, Ltd. UK |
| Texas instrument TI-99/4A cart. | Sudoku | 19?? | Unknown |
| Texas instrument TI-99/4A cart. | Super Demon Attack Model PHM 3219 | 1983 | Imagic, Inc. Los Gatos, CA, USA |
| Texas instrument TI-99/4A cart. | Super Duper | 1984 | Navarone |
