| Sega Genesis cart. |  Championship Pool Model T-87076 | 1993 | Mindscape, Inc. Northbrook, IL, USA 24294 |
| Sega Genesis cart. | Championship Pro-Am Model T-97046 | 1992 | Tradewest, Inc. Corsicana, TX, USA |
| Sega Genesis cart. | Chase H.Q. II Model T-11106 | 1992 | Taito Corp. Japan |
| Sega Genesis cart. | Chavez II Model T-137036 | 1993 | American Softworks Corp. |
| Sega Genesis cart. | Chester Cheetah - Too Cool to Fool Model T-33056 | 1992 | Kaneko USA, Ltd. IL, USA |
| Sega Genesis cart. | Chester Cheetah - Wild Wild Quest Model T-33066 | 1992 | Kaneko USA, Ltd. IL, USA |
| Sega Genesis cart. | Chi Chi's Pro Challenge Golf Model T-70186 | 1993 | Virgin Games Irvine, CA, USA 52145 |
| Sega Genesis cart. |  Chiki Chiki Boys Model 1075 P | 1993 | SEGA of America, Inc. San Francisco, CA, USA |
| Sega Genesis cart. | Chuck Rock II - Son of Chuck Model T-70156 | 1993 | Virgin Games, Ltd. UK 013715 |
| Sega Genesis cart. | Chuck Rock Model 70036 | 1992 | Virgin Games, Ltd. UK 013715 |
| Sega Genesis cart. | Clan of Warriors - Generals of the Yang Family | 2016 | Piko Interactive LLC |
| Sega Genesis cart. | Clay Fighter Model T-125036 | 1994 | Interplay |
| Sega Genesis cart. | Cliffhanger Model T-93036 | 1993 | Sony Imagesoft |
| Sega Genesis cart. | Clue Model T-89016 | 1992 | Parker Bros. Beverly, MA, USA |
| Sega Genesis cart. | Coach K College Basketball Model 7521 | 1995 | EA Sports |
| Sega Genesis cart. | Coffee Crisis Hb | 2017 | Mega Cat Studios |
| Sega Genesis cart. |  Coffee Crisis demo | 2017 | Mega Cat Studios |
| Sega Genesis cart. | College Football USA 96 Model 7491 | 1995 | EA Sports |
| Sega Genesis cart. | College Football USA 97 - The Road to New Orleans Model 7716 | 1996 | EA Sports |
| Sega Genesis cart. | College Football's National Championship II Model 1241 | 1995 | SEGA of America, Inc. San Francisco, CA, USA |
| Sega Genesis cart. | College Football's National Championship Model 1227 | 1994 | SEGA of America, Inc. San Francisco, CA, USA |
| Sega Genesis cart. | College Slam Model T-81576 | 1996 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Sega Genesis cart. | Columns III - Revenge of Columns Model T-23056 | 1993 | Vic Tokai Japan |
| Sega Genesis cart. | Columns Model 1701 | 1990 | SEGA of America, Inc. San Francisco, CA, USA |
| Sega Genesis cart. |  Combat Aces | 199? | Baton Technologies AZ, USA |
| Sega Genesis cart. | Combat Cars Model 3408 | 1994 | Accolade, Inc. San Jose, CA, USA 15605 |
| Sega Genesis cart. | Comix Zone Model 1569 | 1995 | SEGA of America, Inc. San Francisco, CA, USA |
| Sega Genesis cart. | Contra - Hard Corps Model T-95106 | 1994 | Konami Co., Ltd. Japan |
| Sega Genesis cart. | Cool Spot Model T-70196 | 1994 | Virgin Games, Ltd. UK 013715 |
| Sega Genesis cart. | Crack Down Model T-47046 | 1991 | Sage's Creation, Inc. |
| Sega Genesis cart. | Cross Fire Model 20916 | 1991 | Kyugo Japan |
| Sega Genesis cart. | Crusader of Centy Model T-144026 | 1995 | Atlus Soft., Inc. CA, USA |
| Sega Genesis cart. | Crüe Ball Model 7072 | 1993 | Electronic Arts CA, USA 14633 |
| Sega Genesis cart. | Crystal's Pony Tale Model 1544 | 1994 | SEGA of America, Inc. San Francisco, CA, USA |
| Sega Genesis cart. | Curse | 1990 | INTV Corp. |
| Sega Genesis cart. | Custodian P | 2018 | Piko Interactive LLC |
| Sega Genesis cart. | Cyber-Cop Model T-70016 | 1992 | Virgin Games, Ltd. UK 013715 |
| Sega Genesis cart. | CyberBall Model 1109 | 1990 | SEGA of America, Inc. San Francisco, CA, USA |
| Sega Genesis cart. | Cyborg Justice Model 1024 | 1993 | SEGA of America, Inc. San Francisco, CA, USA |
| Sega Genesis cart. | Danny Sullivan's Indy Heat | 199? | Tradewest, Inc. Corsicana, TX, USA |
