| Sega Mega Drive cart. |  Phantasy Star III - Generations of Doom | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Phantasy Star III - Generations of Doom Model 048220 | 1998 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. |  Phantasy Star III - Toki no Keishousha Model G-5503 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Phantasy Star IV - The End of the Millennium Model 1307-50 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Phantom 2040 Model T-139036-50 | 1995 | Viacom New Media Viacom International, Inc. |
| Sega Mega Drive cart. | Phelios Model T-14013 | 1990 | NAMCOT Japan |
| Sega Mega Drive cart. | Pier Solar and the Great Architects Model T-574016-50 Hb | 2010 | WaterMelon |
| Sega Mega Drive cart. | Pinocchio | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Pirates of the Caribbean | 199? | Unknown |
| Sega Mega Drive cart. | Piraty Karibskogo Morya - Na Strannyh Beregah | 199? | Unknown |
| Sega Mega Drive cart. | Pit-Fighter Model 301027-0170 | 1991 | Tengen, Inc. Milpilas, CA, USA |
| Sega Mega Drive cart. | Pit-Fighter Model T-48033 | 1992 | Tengen, Inc. Milpilas, CA, USA |
| Sega Mega Drive cart. | Pitfall - The Mayan Adventure | 1994 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Sega Mega Drive cart. | Planet Message Quiz Model T-19402 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Platinum Collection: Sonic & Knuckles Model FSON096MC | 199? | SEGA OziSoft Australia |
| Sega Mega Drive cart. | Pocahontas | 1996 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Populous | 1991 | Electronic Arts CA, USA 14633 |
| Sega Mega Drive cart. | Populous | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Power Athlete Model T-33033 | 1992 | Kaneko Co., Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Power Drive Model T-79146-50 | 1994 | US Gold, Ltd. Birmingham, England 13442 |
| Sega Mega Drive cart. | PowerMonger Model EM20011 | 1993 | Electronic Arts CA, USA 14633 |
| Sega Mega Drive cart. | Premier Manager | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Premier Manager 97 | 1996 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Prince of Persia | 1993 | Domark Group, Ltd. |
| Sega Mega Drive cart. |  Prince of Persia 2 - The Shadow & the Flame P | 1996 | Titus Gagny, France |
| Sega Mega Drive cart. | Pro Striker Final Stage Model G-5547 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Pro Yakyuu Super League '91 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Probotector Model T-95106-50 | 1994 | Konami Co., Ltd. Japan |
| Sega Mega Drive cart. | Psy-O-Blade Model T-26013 | 1990 | Sigma Enterprises, Inc. Tokyo, Japan |
| Sega Mega Drive cart. | Psycho Pinball | 1994 | Codemasters Soft. Co., Ltd., The 015026 |
| Sega Mega Drive cart. | Puggsy Model T-113016-50 | 1993 | Psygnosis, Ltd. |
| Sega Mega Drive cart. | Pulseman Model G-4098 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Puyo Puyo 2 Model T-66013 | 1994 | Compile |
| Sega Mega Drive cart. | Puyo Puyo Model G-4082 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Pyramid Magic II | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | QuackShot - I Love Donald Duck - Guruzia Ou no Hihou Model G-4054 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | QuackShot starring Donald Duck | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Queen of Poker Club | 199? | Sachen Thin Chen co. Taiwan |
| Sega Mega Drive cart. | R.B.I. Baseball 4 | 1992 | Tengen, Inc. Milpilas, CA, USA |
| Sega Mega Drive cart. | Radical Rex Model T-130026-50 | 1994 | Activision, Inc. Los Angeles, CA, USA 47875 |
