| Sharp X68000 Series 5.25in. disk |  MCHA | 1991 | FNeW |
| Sharp X68000 Series 5.25in. disk | Mega Lo Mania | 1993 | Imagineer Co., Ltd. Japan |
| Sharp X68000 Series 5.25in. disk | Mega Powerful Jangken Pro-68K | 1992 | Gainen Shuppon |
| Sharp X68000 Series 5.25in. disk | Megami de Pon | 1995 | DCS Japan |
| Sharp X68000 Series 5.25in. disk | Mei Kan Toku II | 1988 | JDS |
| Sharp X68000 Series 5.25in. disk | Memory Broken | 1989 | Fukuiinchou |
| Sharp X68000 Series 5.25in. disk | Mercury - The Prime Master | 1991 | Maxima Japan |
| Sharp X68000 Series 5.25in. disk | Messiah 68K | 1988 | Cross Line |
| Sharp X68000 Series 5.25in. disk | Metal Eye 18 | 1993 | Elf Japan |
| Sharp X68000 Series 5.25in. disk | Metal Eye Special Disk 18 | 1993 | Elf Japan |
| Sharp X68000 Series 5.25in. disk | Metal Sight | 1989 | System Sacom Corp. Japan |
| Sharp X68000 Series 5.25in. disk | Metal Unit | 1994 | T&H Project |
| Sharp X68000 Series 5.25in. disk | Metal Unit II Power Unit | 1994 | T&H Project |
| Sharp X68000 Series 5.25in. disk | Meteo Wars | 19?? | Unknown Japan |
| Sharp X68000 Series 5.25in. disk | Meurtre d'un Clown - Doukeshi Satsujin Jiken Model SJTQ-13001 | 1988 | Thinking Rabbit Japan |
| Sharp X68000 Series 5.25in. disk | Mid-Garts Gold | 1989 | Wolf Team Japan |
| Sharp X68000 Series 5.25in. disk | Might and Magic - Book One: Secret of the Inner Sanctum | 1988 | Starcraft, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Might and Magic - Book Two: Gates Two Another World! | 1989 | Starcraft, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Mikkun Fly! Hb | 1991 | Brace |
| Sharp X68000 Series 5.25in. disk | Milk Time | 1991 | System House Oh! Japan |
| Sharp X68000 Series 5.25in. disk | Million Shot | 1993 | IJI Team |
| Sharp X68000 Series 5.25in. disk | Minami no Hiroshi no Eigo Kyoushitsu | 1989 | Todo2 Japan |
| Sharp X68000 Series 5.25in. disk | Mirage | 1992 | Discovery Corp. Japan |
| Sharp X68000 Series 5.25in. disk | Mirage | 199? | Rowan |
| Sharp X68000 Series 5.25in. disk | Missile Command 68K | 1989 | Tiny-Tomo |
| Sharp X68000 Series 5.25in. disk | Missile Command AMA-68K | 1988 | Tiny-Tomo |
| Sharp X68000 Series 5.25in. disk | Mission For Adult | 1990 | Unknown Japan |
| Sharp X68000 Series 5.25in. disk | Missle Command | 1992 | YOH Japan |
| Sharp X68000 Series 5.25in. disk | Missle Command SX-68K | 1992 | Noom Activity |
| Sharp X68000 Series 5.25in. disk | Misty 68K Vol. 1 - Kikai na Zenra Shitai | 1989 | Data West, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Misty 68K Vol. 2 - Unmei no Akugi no Naka De | 1989 | Data West, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Misty 68K Vol. 3 - Satsui no Haikei | 1990 | Data West, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Misty 68K Vol. 4 - Sora he Kikan Mono | 1990 | Data West, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Misty 68K Vol. 5 - Utsukushiki Akuma | 1990 | Data West, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Misty 68K Vol. 6 - Nido Me no Organ | 1990 | Data West, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Misty 68K Vol. 7 - Yami no Naka no Shikisai | 1991 | Data West, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Mobile Suit Gundam - Classic Operation | 1991 | Brother Kougyou Japan |
| Sharp X68000 Series 5.25in. disk | Mogu | 1990 | Phoenix Japan |
| Sharp X68000 Series 5.25in. disk | Mogura Attacker | 1990 | Project Makkusu |
| Sharp X68000 Series 5.25in. disk | Mokona in Space | 1995 | 68 Bank |
