| Nintendo Famicom cart. |  Momotarou Dentetsu | 1988 | Hudson Soft. Hudson Group Japan |
| Nintendo Famicom cart. | Nakajima Satoru F-1 Hero | 1988 | Varie Corp. Japan |
| Nintendo Famicom cart. | Namco Classic | 1988 | NAMCOT Japan |
| Nintendo Famicom cart. | Napoleon Senki | 1988 | Irem Corp. Japan |
| Nintendo Famicom cart. | Nekketsu Koukou Dodgeball Bu Model TJC-ND | 1988 | Technos Japan Corp. Japan |
| Nintendo Famicom cart. | Ninja Ryukenden Model TCF-NY | 1988 | Tecmo, Ltd. Tokyo, Japan |
| Nintendo Famicom cart. | Ninja-kun - Ashura no Shou Model UPL-NJ P | 1988 | UPL Co., Ltd. Universal PlayLand |
| Nintendo Famicom cart. | Nobunaga no Yabou - Zen-Koku-Ban Model KOE-NZ | 1988 | KOEI Co., Ltd. Japan |
| Nintendo Famicom cart. | Paris-Dakar Rally Special | 1988 | CBS Sony Group |
| Nintendo Famicom cart. | Predator | 1988 | Pack-In-Video Co., Ltd. Japan |
| Nintendo Famicom cart. | Pro Yakyuu Family Stadium '88 | 1988 | NAMCOT Japan |
| Nintendo Famicom cart. | Pro Yakyuu? Satsujin Jiken! Model CAP-PV | 1988 | Capcom Co., Ltd. Japan |
| Nintendo Famicom cart. | Rainbow Islands - The Story of Bubble Bobble 2 Model DTF-RL P | 1988 | Taito Corp. Japan |
| Nintendo Famicom cart. | Reigen Doushi Model R59V5917 | 1988 | Pony Canyon, Inc. Japan |
| Nintendo Famicom cart. | Ripple Island Model TEC-RI | 1988 | SUNSOFT Kounan, Japan |
| Nintendo Famicom cart. | Rockman 2 - Dr. Wily no Nazo Model CAP-XR | 1988 | Capcom Co., Ltd. Japan |
| Nintendo Famicom cart. | Rollerball | 1988 | HAL Laboratory, Inc. Japan |
| Nintendo Famicom cart. | Saint Seiya - Ougon Densetsu Kanketsu-hen Model SHI-OK | 1988 | Shinsei |
| Nintendo Famicom cart. | Saiyuuki World Model NMK-KW | 1988 | JALECO Co., Ltd. Japan |
| Nintendo Famicom cart. | Salad no Kuni no Tomato Hime Model HFC-RT | 1988 | Hudson Soft. Hudson Group Japan |
| Nintendo Famicom cart. | Sanada Juu Yuushi | 1988 | Kemco, Ltd. |
| Nintendo Famicom cart. | Sangokushi - Chuugen no Hasha | 1988 | NAMCOT Japan |
| Nintendo Famicom cart. | Sangokushi Model KOE-IS | 1988 | KOEI Co., Ltd. Japan |
| Nintendo Famicom cart. | Satsui no Kaisou - Power Soft Satsujin Jiken | 1988 | HAL Laboratory, Inc. Japan |
| Nintendo Famicom cart. | Sensha Senryaku - Sabaku no Kitsune | 1988 | Kemco, Ltd. |
| Nintendo Famicom cart. | Shogun | 1988 | HECT Hector Japan |
| Nintendo Famicom cart. | Shoukoushi Ceddie | 1988 | Fuji TV |
| Nintendo Famicom cart. | Shuang Xiang Pao | 1988 | Bit Corp. |
| Nintendo Famicom cart. | Shui Guo Li | 1988 | Bit Corp. |
| Nintendo Famicom cart. | Soccer League - Winner's Cup | 1988 | Data East Corp. Japan |
| Nintendo Famicom cart. |  Strider Hiryu | 1988 | Capcom Co., Ltd. Japan |
| Nintendo Famicom cart. | Sukeban Deka III | 1988 | Toei Animation Co., Ltd. Japan |
| Nintendo Famicom cart. | Super Black Onyx | 1988 | BPS Bullet-Proof Soft. Japan |
| Nintendo Famicom cart. | Super Dyna'Mix Badminton | 1988 | VAP Game Japan |
| Nintendo Famicom cart. | Super Mario Bros. 3 Model HVC-UM | 1988 | Nintendo Co., Ltd. Japan |
| Nintendo Famicom cart. | Super Pinball Model CDS-PJ | 1988 | Coconuts Japan |
| Nintendo Famicom cart. | Super Real Baseball '88 Model VAP-BG | 1988 | VAP Game Japan |
| Nintendo Famicom cart. | Taiyou no Shinden - Asteka II Model TKS-GS | 1988 | Tokyo Shoseki |
| Nintendo Famicom cart. | Takeda Shingen | 1988 | Hot-B Japan |
| Nintendo Famicom cart. | Takeshi no Sengoku Fuuunji Model TFC-TSF-5800 | 1988 | Taito Corp. Japan |
