| Nintendo Famicom cart. |  Dragon Spirit - Aratanaru Densetsu Model NAM-DS-5200 | 1989 | NAMCOT Japan |
| Nintendo Famicom cart. | Dragon Unit Model ATH-ZX | 1990 | Athena Co., Ltd. Japan |
| Nintendo Famicom cart. | Dragon Wars Model KSC-Z9 | 1991 | Kemco, Ltd. |
| Nintendo Famicom cart. | Dragon's Lair | 1991 | Epic/Sony Records Sony Music Ent., Inc. Japan |
| Nintendo Famicom cart. | Dream Fighter | 1993 | Asder Electronic Co., Ltd. Taiwan |
| Nintendo Famicom cart. | Dream Master | 1992 | NAMCOT Japan |
| Nintendo Famicom cart. | Druaga no Tou Model NTD-4900 P | 1985 | NAMCOT Japan |
| Nintendo Famicom cart. | Du Shen | 19?? | XianFeng Katong China |
| Nintendo Famicom cart. | Du Shen Model ES-1105 | 19?? | Waixing Computer & Technology Co., Ltd. China |
| Nintendo Famicom cart. | Duck | 19?? | Unknown |
| Nintendo Famicom cart. | Duck Hunt Model HVC-DH | 1984 | Nintendo Co., Ltd. Japan |
| Nintendo Famicom cart. |  Dump Matsumoto P | 198? | Unknown |
| Nintendo Famicom cart. | Dungeon & Magic - Swords of Element Model NAT-DM | 1989 | Natsume, Inc. Japan |
| Nintendo Famicom cart. | Dungeon Hourouki | 199? | ASCII Corp. Japan |
| Nintendo Famicom cart. | Dungeon Kid Model BTC-7D | 1990 | Quest |
| Nintendo Famicom cart. | Duo Bao Xiao Ying Hao - Guang Ming Yu An Hei Chuan Shuo Model ES-1021 | 19?? | Waixing Computer & Technology Co., Ltd. China |
| Nintendo Famicom cart. | Dynamite Batman | 1991 | SUNSOFT Kounan, Japan |
| Nintendo Famicom cart. | Dynamite Bowl Model FS-2005G | 1987 | Toemiland |
| Nintendo Famicom cart. | E Luo Si Fang Kuai Hb | 200? | Yan Yanhuo China |
| Nintendo Famicom cart. | Earthworm Jim 2 Model NT849 P | 1996 | Shin-Shin Electronic Co., Ltd. |
| Nintendo Famicom cart. | Education Computer 2000 48 in 1 | 1999 | Unknown Russia |
| Nintendo Famicom cart. | Eggerland - Meikyuu no Fukkatsu Model HAL-EG | 1988 | HAL Laboratory, Inc. Japan |
| Nintendo Famicom cart. | Egypt Model HUM-E9 | 1991 | Human Ent. Japan |
| Nintendo Famicom cart. | Elevator Action Model TF-4900 P | 1985 | Taito Corp. Japan |
| Nintendo Famicom cart. | Elysion | 1988 | Tokyo Shoseki |
| Nintendo Famicom cart. | Emo Yan no 10 Bai Pro Yakyuu Model HCT-IB/005 | 1989 | HECT Hector Japan |
| Nintendo Famicom cart. | Er Zhan Zhi Jing Dian Zhan Yi | 199? | HengGedianzi China |
| Nintendo Famicom cart. | Erika to Satoru no Yume Bouken Model NAM-YB-4900 | 1988 | NAMCOT Japan |
| Nintendo Famicom cart. | Erunaaku no Zaihou Model TCC-EL | 1987 | Towa Chiki Japan |
| Nintendo Famicom cart. | Esper Boukentai Model JF-15 | 1987 | JALECO Co., Ltd. Japan |
| Nintendo Famicom cart. | Esper Dream 2 - Aratanaru Tatakai Model RC861 | 1992 | Konami Co., Ltd. Japan |
| Nintendo Famicom cart. | Europa Sensen | 1996 | Waixing Computer & Technology Co., Ltd. China |
| Nintendo Famicom cart. | Everquest - Wujìn de Renwu | 199? | Waixing Computer & Technology Co., Ltd. China |
| Nintendo Famicom cart. | Excitebike Model HVC-EB | 1984 | Nintendo Co., Ltd. Japan |
| Nintendo Famicom cart. | Exciting Boxing | 1987 | Konami Industry Co., Ltd. Japan |
| Nintendo Famicom cart. | Exciting Rally - World Rally Championship Model VRE-E2 | 1992 | Kaken Japan |
| Nintendo Famicom cart. | Exed Exes Model GTS-EE P | 1985 | Tokuma Shoten Intermedia, Inc. Japan |
| Nintendo Famicom cart. | Exerion Model JF-01 P | 1985 | JALECO Co., Ltd. Japan |
| Nintendo Famicom cart. | F-1 Race Model HVC-FR-JPN | 1984 | Nintendo Co., Ltd. Japan |
| Nintendo Famicom cart. | F-1 Sensation Model KDS-FE | 1993 | Konami Co., Ltd. Japan |
