| Atari 2600 cart. |  Spacechase Model AP2001 | 1981 | Apollo, Inc. Richardson, TX, USA |
| Atari 2600 cart. |  Spacechase PAL Model AP-2001 | 1981 | Apollo, Inc. Richardson, TX, USA |
| Apple II 5.25 disk | Ernie's Quiz | 1981 | Apple Computer, Inc. |
| Apple II 5.25 disk | Instant Zoo | 1981 | Apple Computer, Inc. |
| Apple II 5.25 disk | Magic Spells | 1981 | Apple Computer, Inc. |
| Apple II 5.25 disk | Mix and Match | 1981 | Apple Computer, Inc. |
| Apple II 5.25 disk | Moptown | 1981 | Apple Computer, Inc. |
| Apple II 5.25 disk | Spotlight | 1981 | Apple Computer, Inc. |
| Applied Concepts Great Game Machine mod. | Capablanca Edition - Master Chess Endgame | 1981 | Applied Concepts, Inc. |
| Applied Concepts Great Game Machine mod. | Gruenfeld Edition - Master Chess Openings | 1981 | Applied Concepts, Inc. |
| Applied Concepts Great Game Machine mod. | Morphy Edition - Master Chess | 1981 | Applied Concepts, Inc. |
| Applied Concepts Great Game Machine mod. | Odin Edition - Master Reversi | 1981 | Applied Concepts, Inc. |
| Atari 2600 cart. | Box-Champion Model 711 002-715 | 1981 | Ariolasoft Germany |
| Atari 2600 cart. | Das Verrückte Huhn Model 711 009-720 | 1981 | Ariolasoft Germany |
| Atari 2600 cart. | Dragster Rennen Model 711 001-715 | 1981 | Ariolasoft Germany |
| Atari 2600 cart. | Duell im Weltall Model 711 008-720 | 1981 | Ariolasoft Germany |
| Atari 2600 cart. | Kaboom - Schneller Als der Knall Model 711 010-720 | 1981 | Ariolasoft Germany |
| Atari 2600 cart. | Lasso-Helden Model 711 011-715 | 1981 | Ariolasoft Germany |
| Atari 2600 cart. | Schneller Als der Hai Model 711 004-715 | 1981 | Ariolasoft Germany |
| Arcade Video game | Space Train | 1981 | Armenia, Ltd. |
| Arcade Video game | War of the Bugs or Monsterous Manouvers in a Mushroom Maze | 1981 | Armenia, Ltd. |
| Atari 400/800 cass. | Cypher Bowl | 1981 | ArtSci |
| Sinclair ZX-81 cass. | 1K Games Pack | 1981 | Artic Computing, Ltd. |
| Sinclair ZX-81 cass. | Adventure A - Planet of Death | 1981 | Artic Computing, Ltd. |
| Jupiter Ace cass. | Adventure A - Planet of Death | 1981 | Artic Computing, Ltd. |
| Sinclair ZX-81 cass. | Adventure B - Inca Curse | 1981 | Artic Computing, Ltd. |
| Sinclair ZX-81 cass. | ZX Bug | 1981 | Artic Computing, Ltd. |
| Sinclair ZX-81 cass. | ZX Chess II | 1981 | Artic Computing, Ltd. |
| Watch game | Cosmic Wars | 1981 | Artron |
| Atari 400/800 disk | Cranston Manor Adventure | 1981 | Artworx Soft. Co., Inc. |
| Atari 400/800 cass. | Encounter at Questar IV | 1981 | Artworx Soft. Co., Inc. |
| Atari 400/800 cass. | Giant Slalom | 1981 | Artworx Soft. Co., Inc. |
| CP/M 8in. disk |  Hearts 1.5 | 1981 | Artworx Soft. Co., Inc. |
| Atari 400/800 cass. | Space Trap | 1981 | Artworx Soft. Co., Inc. |
| RCA COSMAC VIP type-in | Baseball | 1981 | Association of Computer Experimenters |
| RCA COSMAC VIP type-in | Kaleidoscopic Life | 1981 | Association of Computer Experimenters |
| RCA COSMAC VIP type-in | Kingdom - A Tiny Basic Simulation Game | 1981 | Association of Computer Experimenters |
| RCA COSMAC ELF type-in | Simon ELF Update | 1981 | Association of Computer Experimenters |
| RCA COSMAC VIP type-in | Test your Reflex | 1981 | Association of Computer Experimenters |
| Bally Astrocade type-in | Count the Boxes | 1981 | Astrocade, Inc. |
