| Nintendo DS cart. |  Bokujou Monogatari - Colobocle Station | 2005 | Marvelous Interactive, Inc. |
| Nintendo DS cart. | Bomberman | 2005 | Hudson Soft. Hudson Group Japan |
| Nintendo DS cart. | Bomberman Model NTR-ABME-USA | 2005 | Ubisoft, Inc. San Francisco, CA, USA 08888 |
| Nintendo DS cart. | Bomberman Model NTR-ABMP-EUR | 2005 | Ubisoft Ent. Montreuil sous Bois, France |
| Nintendo DS cart. | Brain Boost - Beta Wave | 2005 | InterChannel, Ltd. |
| Nintendo DS cart. | Brain Boost - Gamma Wave | 2005 | InterChannel, Ltd. |
| Nintendo DS cart. | Bubble Bobble Revolution | 2005 | Rising Star Games, Ltd. UK |
| Nintendo DS cart. | Burnout Legends Model NTR-ABOE-USA | 2005 | Electronic Arts CA, USA 14633 |
| Nintendo DS cart. |  Burnout Legends Model NTR-ABOP-EUR | 2005 | Electronic Arts CA, USA 14633 |
| Nintendo DS cart. | Castlevania - Dawn of Sorrow Model NTR-ACVE-USA | 2005 | Konami Digital Ent. Co., Ltd. |
| Nintendo DS cart. | Castlevania - Dawn of Sorrow Model NTR-ACVP-EUR | 2005 | Konami Digital Ent. Co., Ltd. |
| Nintendo DS cart. | Catch! Touch! Yoshi! Model NTR-AGFJ-JPN | 2005 | Nintendo Co., Ltd. Japan |
| Nintendo DS cart. | Chou Shittou Caduceus Model NTR-AKDJ-JPN | 2005 | Atlus Co., Ltd. Japan |
| Nintendo DS cart. | Daigasso! Band Brothers Request Selection Model NTR-ZBBJ-JPN | 2005 | Nintendo Co., Ltd. Japan |
| Nintendo DS cart. | Daredemo Asobi Taizen | 2005 | Nintendo Co., Ltd. Japan |
| Nintendo DS cart. | Devilish - Ball Bounder Model NTR-ADVJ-JPN | 2005 | Starfish-SD, Inc. Japan |
| Nintendo DS cart. | Dig Dug - Digging Strike | 2005 | NAMCO Hometek, Ltd. USA |
| Nintendo DS cart. | Dragon Ball Z - Supersonic Warriors 2 | 2005 | Atari, Inc. NY, USA |
| Nintendo DS cart. | DreamWorks Madagascar Model NTR-AMGE-USA | 2005 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo DS cart. | DreamWorks Madagascar Model NTR-AMGJ-JPN | 2005 | Bandai Co., Ltd. Japan |
| Nintendo DS cart. | DreamWorks Madagascar Model NTR-AMGP-EUR | 2005 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo DS cart. | Electroplankton Model NTR-ATIJ-JPN | 2005 | Nintendo Co., Ltd. Japan |
| Nintendo DS cart. | Elf Bowling 1&2 Model NTR-AEBE-USA | 2005 | Ignition Ent., Ltd. |
| Nintendo DS cart. | Famicom Wars DS | 2005 | Nintendo Co., Ltd. Japan |
| Nintendo DS cart. | Ford Racing 3 | 2005 | Destination Soft. |
| Nintendo DS cart. | Frogger - Helmet Chaos Model NTR-AFGE-USA | 2005 | Konami Digital Ent. Co., Ltd. |
| Nintendo DS cart. | Ganbare Goemon - Toukai Douchuu Ooedo Tengurigaeshi no Maki Model NTR-A5EJ-JPN | 2005 | Konami Corp. Japan |
| Nintendo DS cart. | GoldenEye - Rogue Agent | 2005 | Electronic Arts CA, USA 14633 |
| Nintendo DS cart. | Gyakuten Saiban - Yomigaeru Gyakuten Model NTR-AGYJ-JPN | 2005 | Capcom Co., Ltd. Japan |
| Nintendo DS cart. | Gyakuten Saiban - Yomigaeru Gyakuten Model NTR-AGYJ-JPN | 2005 | Capcom Co., Ltd. Japan |
| Nintendo DS cart. | Hagane no Renkinjutsushi - Dual Sympathy | 2005 | Bandai Co., Ltd. Japan |
| Nintendo DS cart. | Harry Potter and the Goblet of Fire Model NTR-AHPE-USA | 2005 | Electronic Arts CA, USA 14633 |
| Nintendo DS cart. | James Pond 2 - Codename: RoboCod Model NTR-AJPP-UKV | 2005 | Play It |
| Nintendo DS cart. | Jump Superstars Model NTR-AJSJ-JPN | 2005 | Nintendo Co., Ltd. Japan |
| Nintendo DS cart. | Kahashima Ryuuta Kyouju no Nou wo Kitaeru Otona no DS Training for Adults | 2005 | Nintendo Co., Ltd. Japan |
| Nintendo DS cart. | Kenshuui Tendou Dokuta 2 - Inochi no Tenbin | 2005 | Spike Japan |
| Nintendo DS cart. | Kim Possible - Kimmunicator Model NTR-AKPE-USA | 2005 | Buena Vista Games |
| Nintendo DS cart. | Lost in Blue - Futari no Survival Life | 2005 | Konami Corp. Japan |
| Nintendo DS cart. | Lost in Blue Model NTR-ASKE-USA | 2005 | Konami Digital Ent. Co., Ltd. |
| Nintendo DS cart. | Lost in Blue Model NTR-ASKP-EUR | 2005 | Konami Europe GmbH Germany |
