| Sega Mega Drive cart. |  Magical Hat no Buttobi Tabo! Daibouken Model G-4041 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | MegaPanel | 1990 | NAMCOT Japan |
| Sega Mega Drive cart. | Michael Jackson's Moonwalker Model G-4028 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | MUSHA Aleste Model T-35013 | 1990 | Toaplan Co., Ltd. Tokyo, Japan |
| Sega Mega Drive cart. |  Mystic Defender Model 1011-50 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Mystic Defense | 1990 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | On Dal Jang Goon | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Phantasy Star II | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Phantasy Star II Model 048.170 | 1990 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Phantasy Star III - Toki no Keishousha Model G-5503 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Phelios Model T-14013 | 1990 | NAMCOT Japan |
| Sega Mega Drive cart. | Psy-O-Blade Model T-26013 | 1990 | Sigma Enterprises, Inc. Tokyo, Japan |
| Sega Mega Drive cart. | Rainbow Islands Extra Model T-11073 | 1990 | Taito Corp. Japan |
| Sega Mega Drive cart. | Rastan Saga II Model T-11043 | 1990 | Taito Corp. Japan |
| Sega Mega Drive cart. |  Road Busters | 1990 | Telenet Japan |
| Sega Mega Drive cart. | Same! Same! Same! Model T-40013 | 1990 | Toaplan Co., Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shadow Dancer - The Secret of Shinobi Model G-4043 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shijou Saidai no Soukoban Model T-25023 | 1990 | NCS Corp. Nippon Computer Systems Japan |
| Sega Mega Drive cart. | Shiten-Myooh Model T-26023 | 1990 | Sigma Enterprises, Inc. Tokyo, Japan |
| Sega Mega Drive cart. | Sorcerian Model G-4504 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Space Invaders 90 Model T-11053 | 1990 | Taito Corp. Japan |
| Sega Mega Drive cart. | Star Cruiser Model T-25063 | 1990 | NCS Corp. Nippon Computer Systems Japan |
| Sega Mega Drive cart. | Stormlord Model T-49113 | 1990 | Micro World |
| Sega Mega Drive cart. | Strider Hiryu Model G-4037 P | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Strider II | 1990 | US Gold, Ltd. Birmingham, England 13442 |
| Sega Mega Drive cart. | Super Futebol | 1990 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Super Hang-On | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Super Hang-On Model 042360 | 1990 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Super League | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Super Monaco GP | 1990 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Super Monaco GP Model G-4026 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Super Real Basketball Model G-4021 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Super Thunder Blade | 1990 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Super Thunder Blade | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Sword of Sodan P | 1990 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Sword of Vermilion | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Tel-Tel Mahjong Model T-15033 | 1990 | SUNSOFT Kounan, Japan |
| Sega Mega Drive cart. | Tel-Tel Stadium Model T-15013 | 1990 | SUNSOFT Kounan, Japan |
| Sega Mega Drive cart. | The New Zealand Story Model T-11013 | 1990 | Taito Corp. Japan |
| Sega Mega Drive cart. | The Revenge of Shinobi | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
