| Sega Mega Drive cart. |  Crüe Ball Model EM20005 | 1993 | Electronic Arts Victor, Inc. Japan |
| Sega Mega Drive cart. |  Dashin' Desperadoes | 1993 | Data East Corp. Japan |
| Sega Mega Drive cart. |  Davis Cup World Tour | 1993 | Tengen, Inc. Milpilas, CA, USA |
| Sega Mega Drive cart. | Desert Strike - Return to the Gulf Model E224SMXI | 1993 | Electronic Arts CA, USA 14633 |
| Sega Mega Drive cart. | Desert Strike - Return to the Gulf Model EM20010 | 1993 | Electronic Arts Victor, Inc. Japan |
| Sega Mega Drive cart. | Devil Crash MD Model T-18053 | 1993 | Tecno Soft. TechnoSoft Japan |
| Sega Mega Drive cart. | Disney's Aladdin | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Doraemon - Yume Dorobou to 7-nin no Gozans Model G-4094 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Double Hits: Psycho Pinball + Micro Machines Model T-120176-50 | 1993 | Codemasters Soft. Co., Ltd., The 015026 |
| Sega Mega Drive cart. | Dr. Robotnik's Mean Bean Machine Model 044860 | 1993 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Dr. Robotnik's Mean Bean Machine Model 1706-50 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Dragon - The Bruce Lee Story | 1993 | Virgin Interactive Ent., Ltd. UK 013715 |
| Sega Mega Drive cart. | Dragon's Revenge Model T-48143 | 1993 | Tengen, Inc. Milpilas, CA, USA |
| Sega Mega Drive cart. | Dune II - Battle for Arrakis Model T-70246-50 | 1993 | Virgin Interactive Ent., Ltd. UK 013715 |
| Sega Mega Drive cart. | Dune II - Kampf um den Wustenplaneten | 1993 | Virgin Interactive Ent., Ltd. UK 013715 |
| Sega Mega Drive cart. | Dyna Brothers 2 Model T-68063 | 1993 | CRI CSK Research Institute Japan |
| Sega Mega Drive cart. | EA Sports Double Header Model E187SMXI | 1993 | EA Sports |
| Sega Mega Drive cart. | Ecco the Dolphin Asian Version | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ecco the Dolphin Model 044360 | 1993 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Ecco the Dolphin Model G-4106 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Eliminate Down Model T-73033 | 1993 | Soft Vision Japan |
| Sega Mega Drive cart. | Eternal Champions Model 047010 | 1993 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Eternal Champions Model 1145-50 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Eternal Champions Model 1145 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Europa Sensen Model T-76113 | 1993 | KOEI Co., Ltd. Japan |
| Sega Mega Drive cart. | Ex-Ranza Model G-4097 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | F-15 Strike Eagle II Model T-104036-50 | 1993 | MicroProse, Ltd. Bristol, UK 015352 |
| Sega Mega Drive cart. | F-22 Interceptor | 1993 | Electronic Arts CA, USA 14633 |
| Sega Mega Drive cart. | F1 | 1993 | Tengen, Inc. Milpilas, CA, USA |
| Sega Mega Drive cart. | F1 World Championship Edition Model T-88146-50 | 1993 | Domark Group, Ltd. |
| Sega Mega Drive cart. | Fantastic Dizzy | 1993 | Codemasters Soft. Co., Ltd., The 015026 |
| Sega Mega Drive cart. | Fatal Fury P | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Flashback Model 79066 | 1993 | US Gold, Ltd. Birmingham, England 13442 |
| Sega Mega Drive cart. | Flashback Model T-15083 | 1993 | SUNSOFT Kounan, Japan |
| Sega Mega Drive cart. | Fun'n Games | 1993 | Sony Imagesoft |
| Sega Mega Drive cart. | G-LOC Air Battle Model G-4079 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Garou Densetsu - Shukumei no Tatakai Model G-4100 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Gauntlet IV Model T-48216-50 | 1993 | Tengen, Inc. Milpilas, CA, USA |
| Sega Mega Drive cart. | Gauntlet Model T-48123 | 1993 | Tengen, Inc. Milpilas, CA, USA |
| Sega Mega Drive cart. | Gods Model T-119036 | 1993 | Accolade, Inc. San Jose, CA, USA 15605 |
