| Sharp X68000 Series 5.25in. disk |  Märchen Maze Model GS-163 P | 1991 | SPS Japan |
| Sharp X68000 Series 5.25in. disk | MCHA | 1991 | FNeW |
| Sharp X68000 Series 5.25in. disk | Mercury - The Prime Master | 1991 | Maxima Japan |
| Sharp X68000 Series 5.25in. disk | Mikkun Fly! Hb | 1991 | Brace |
| Sharp X68000 Series 5.25in. disk | Milk Time | 1991 | System House Oh! Japan |
| Sharp X68000 Series 5.25in. disk | Misty 68K Vol. 7 - Yami no Naka no Shikisai | 1991 | Data West, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Mobile Suit Gundam - Classic Operation | 1991 | Brother Kougyou Japan |
| Sharp X68000 Series 5.25in. disk | Momotarou Gaiden Momokochan Fight! | 1991 | Todo2 Japan |
| Sharp X68000 Series 5.25in. disk | Mon Mon Shinkei Suijaku 3 | 1991 | Todo2 Japan |
| Sharp X68000 Series 5.25in. disk | Namachuukei 68 Model RA956 | 1991 | Konami Industry Co., Ltd. Japan |
| Sharp X68000 Series 5.25in. disk | Naniwa Do Konjou Series Nouten Chokudake! 3 | 1991 | Iron Gear |
| Sharp X68000 Series 5.25in. disk | New 3D Golf Simulation - Eight Lakes G.C. Model TED-116 | 1991 | T&E Soft. Japan |
| Sharp X68000 Series 5.25in. disk | New 3D Golf Simulation - Harukanaru Augusta Model TED-113 | 1991 | T&E Soft. Japan |
| Sharp X68000 Series 5.25in. disk | Niko² | 1991 | Wolf Team Japan |
| Sharp X68000 Series 5.25in. disk | Noble Mind | 1991 | Brother Kougyou Japan |
| Sharp X68000 Series 5.25in. disk | Nobunaga no Yabou - Bushou Fuuunroku Model KN10111070 | 1991 | KOEI Co., Ltd. Japan |
| Sharp X68000 Series 5.25in. disk | Nostalgia 1907 | 1991 | Sur De Wave Japan |
| Sharp X68000 Series 5.25in. disk | Oh! X 1991 - Ginga Shinnen PRO-68k | 1991 | Softbank Corp. Japan |
| Sharp X68000 Series 5.25in. disk | Oh! X 1991.05 - Ougou Shuukan PRO-68K | 1991 | Softbank Corp. Japan |
| Sharp X68000 Series 5.25in. disk | Olteus II | 1991 | Brother Kougyou Japan |
| Sharp X68000 Series 5.25in. disk | Parodius Da! Model RA955 P | 1991 | Konami Industry Co., Ltd. Japan |
| Sharp X68000 Series 5.25in. disk | Phalanx | 1991 | Zoom Japan |
| Sharp X68000 Series 5.25in. disk | Phantasie IV - The Bird of Heroes | 1991 | Starcraft, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Port Tower Monogatari | 1991 | Unknown Japan |
| Sharp X68000 Series 5.25in. disk | Potton Hb | 1991 | Chinchilla Japan |
| Sharp X68000 Series 5.25in. disk | PowerMonger | 1991 | Imagineer Co., Ltd. Japan |
| Sharp X68000 Series 5.25in. disk | Present | 1991 | Orange House Japan |
| Sharp X68000 Series 5.25in. disk | Pretty Doll | 1991 | System House Oh! Japan |
| Sharp X68000 Series 5.25in. disk | Prince of Persia Model 181289 | 1991 | Broderbund Japan |
| Sharp X68000 Series 5.25in. disk | Pro Soccer 68 | 1991 | Imagineer Co., Ltd. Japan |
| Sharp X68000 Series 5.25in. disk | Puzzle | 1991 | Unknown Japan |
| Sharp X68000 Series 5.25in. disk | Puzzle 15 | 1991 | Unknown Japan |
| Sharp X68000 Series 5.25in. disk | Quarterstaff - The Tomb of Setmoth | 1991 | Starcraft, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Quieazum Biwahoshi Quiz System | 1991 | Biwahosi Soft. |
| Sharp X68000 Series 5.25in. disk | Quintia Road | 1991 | Great Japan |
| Sharp X68000 Series 5.25in. disk | Quiz Ikasete... | 1991 | Software House Aladdin Japan |
| Sharp X68000 Series 5.25in. disk | Ramune Club | 1991 | Mog-Net |
| Sharp X68000 Series 5.25in. disk | Rance III - Leazas Kanraku 18 | 1991 | Alicesoft Japan |
| Sharp X68000 Series 5.25in. disk | Rance III - Leazas Kanraku Option Set | 1991 | Alicesoft Japan |
| Sharp X68000 Series 5.25in. disk | Real | 1991 | Phoenix Japan |
