| NEC PC-9801 Series 5.25in. disk |  Dragon Knight III for Adult 18 | 1991 | Elf Japan |
| NEC PC-9801 Series 5.25in. disk | Drakkhen | 1991 | Epic/Sony Records Sony Music Ent., Inc. Japan |
| NEC PC-9801 Series 5.25in. disk | Duel - Kawanakajima Scenario | 1991 | KSK Kure Soft. Koubou Japan |
| NEC PC-9801 Series 5.25in. disk | Dungeon Buster 2 Revive 18 | 1991 | Great Japan |
| NEC PC-9801 Series 5.25in. disk | Dungeon Harlem | 1991 | Heart Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Dynamo | 1991 | Bio 100% Japan |
| NEC PC-9801 Series 5.25in. disk | Eikan wa Kimi ni 2 - Koukou Yakyuu Zenkoku Taikai | 1991 | Artdink Corp. Japan |
| NEC PC-9801 Series 5.25in. disk | Eisei Meijin II Model RA607 | 1991 | Konami Co., Ltd. Japan |
| NEC PC-9801 Series 5.25in. disk | Elle 18 | 1991 | Elf Japan |
| NEC PC-9801 Series 5.25in. disk | eXOn | 1991 | Softec Japan |
| NEC PC-9801 Series 5.25in. disk |  eXOn Demo | 1991 | Softec Japan |
| NEC PC-9801 Series 5.25in. disk | Fairytale Kaizokuban | 1991 | Fairytale Japan |
| NEC PC-9801 Series 5.25in. disk | Fall | 1991 | Queensoft Japan |
| NEC PC-9801 Series 5.25in. disk | Falla no Jikekkai | 1991 | Heart Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Flash Point | 1991 | Dot Kikaku Japan |
| NEC PC-9801 Series 5.25in. disk | Flash Point 2 | 1991 | Dot Kikaku Japan |
| NEC PC-9801 Series 5.25in. disk | Flash Point 3 | 1991 | Dot Kikaku Japan |
| NEC PC-9801 Series 5.25in. disk | Foreigner | 1991 | Great Japan |
| NEC PC-9801 Series 5.25in. disk | Foxy 2 18 | 1991 | Elf Japan |
| NEC PC-9801 Series 5.25in. disk | Fray - In Magical Adventure Model 15455 | 1991 | Micro Cabin Co. Japan |
| NEC PC-9801 Series 5.25in. disk | Fuga Selection 1: Calcutta & Maze Quest | 1991 | Fuga System Japan |
| NEC PC-9801 Series 5.25in. disk | Fujiko Fujio no Warau Salesman | 1991 | Compile |
| NEC PC-9801 Series 5.25in. disk | Fujiko Fujio no Warau Salesman 2 | 1991 | Compile |
| NEC PC-9801 Series 5.25in. disk | Future Wars - Toki no Boukensha | 1991 | Starcraft, Inc. Japan |
| NEC PC-9801 Series 5.25in. disk | G Senryaku | 1991 | Great Japan |
| NEC PC-9801 Series 5.25in. disk | Gakuen Toshi Z | 1991 | Striker Japan |
| NEC PC-9801 Series 5.25in. disk | Ge-Ten - Sengoku Nobunagaden Geten | 1991 | Hokusho Japan |
| NEC PC-9801 Series 5.25in. disk | Gidyy | 1991 | Heart Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Ginga Eiyuu Densetsu II DX+Kit | 1991 | Bothtec, Inc. Japan |
| NEC PC-9801 Series 5.25in. disk | Ginga Senshin Guynarock - Galactic Guardian | 1991 | TechnoGrad Japan |
| NEC PC-9801 Series 5.25in. disk | Go III | 1991 | ASCII Corp. Japan |
| NEC PC-9801 Series 5.25in. disk | Grand Prix Circus Power Up Kit | 1991 | WestSide Softhouse Japan |
| NEC PC-9801 Series 5.25in. disk | Group X | 1991 | Compac Japan |
| NEC PC-9801 Series 5.25in. disk | Gunyuu Sangokushi Model E-G263 | 1991 | Enix, Ltd. Japan |
| NEC PC-9801 Series 5.25in. disk | Guy - Kill The Target | 1991 | DoA Japan |
| NEC PC-9801 Series 5.25in. disk | Hacchake Ayayo-san 3 - Watashi, Icchattan Desu - Ayayo's Life After | 1991 | Hard Japan |
| NEC PC-9801 Series 5.25in. disk | Hacchake Ayayo-san 3 Omake Disk - Bucchake Tomoko-san - Ochiteimasu, Doko made mo | 1991 | Hard Japan |
| NEC PC-9801 Series 5.25in. disk | Hatris | 1991 | BPS Bullet-Proof Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Hoshi no Suna Monogatari 18 | 1991 | DO Corp. Japan |
| NEC PC-9801 Series 5.25in. disk | Hot Print | 1991 | Peach Soft. Japan |
