| Nintendo Game Boy Color cart. |  Cross Country Racing Model DMG-ARLP-EUR | 2000 | Konami Co., Ltd. Japan |
| Nintendo Game Boy Color cart. |  Cruis'n Exotica Model CGB-BXOE-USA | 2000 | Midway Home Ent. |
| Nintendo Game Boy Color cart. | Crystalis Model CGB-AYJE-USA | 2000 | Nintendo of America, Inc. USA 45496 |
| Nintendo Game Boy Color cart. | CyberTiger Model CGB-BCTE-USA | 2000 | Electronic Arts CA, USA 14633 |
| Nintendo Game Boy Color cart. | CyberTiger Model CGB-BCTP-UKV | 2000 | Electronic Arts CA, USA 14633 |
| Nintendo Game Boy Color cart. | Cyborg Kuro-chan - Devil Fukkatsu Model CGB-BSKJ-JPN | 2000 | Konami Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Cyborg Kuro-chan 2 - White Woods no Gyakushuu Model CGB-BSBJ-JPN | 2000 | Konami Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Daa! Daa! Daa! Totsuzen Card de Battle de Uranai de! Model CGB-BDOJ-JPN | 2000 | Video System Co., Ltd. Kyoto, Japan |
| Nintendo Game Boy Color cart. | Daffy Duck - Subette Koron de Taikin Mochi Model DMG-AD7J-JPN | 2000 | SUNSOFT Kounan, Japan |
| Nintendo Game Boy Color cart. | Daikatana Model CGB-A22X-EUR | 2000 | Kemco, Ltd. |
| Nintendo Game Boy Color cart. | Daikatana Model CGB-A22Y-EUU | 2000 | Kemco, Ltd. |
| Nintendo Game Boy Color cart. | Daiku no Gen-san - Kachikachi no Tonkachi ga Kachi Model DMG-BGNJ-JPN | 2000 | GAPS, Inc. |
| Nintendo Game Boy Color cart. | Dance Dance Revolution GB Model CGB-BDGJ-JPN | 2000 | Konami Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Dance Dance Revolution GB2 Model CGB-BD2J-JPN | 2000 | Konami Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Das Geheimnis der Happy Hippo-Insel Model CGB-BHOD-NOE | 2000 | Infogrames Europe 546430 |
| Nintendo Game Boy Color cart. | Data-Navi Pro Yakyuu Model CGB-A89J-JPN | 2000 | Now Production |
| Nintendo Game Boy Color cart. | Dave Mirra Freestyle BMX Model CGB-BMXE-USA | 2000 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Nintendo Game Boy Color cart. | Dave Mirra Freestyle BMX Model CGB-BMXP-EUR | 2000 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Nintendo Game Boy Color cart. | Deadly Skies Model CGB-BDLP-EUR | 2000 | Konami Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Dear Daniel no Sweet Adventure - Kitty-chan o Sagashite Model DMG-BSAJ-JPN | 2000 | Imagineer Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Dejiko no Mahjong Party Model CGB-BQSJ-JPN | 2000 | King Records Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Densha de Go! 2 Model CGB-B82J-JPN | 2000 | CyberFront Corp. Japan |
| Nintendo Game Boy Color cart. | Der König der Löwen - Simbas grosses Abenteuer Model CGB-BLKD-NOE | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Nintendo Game Boy Color cart. | Dexter's Laboratory - Robot Rampage Model CGB-BROE-USA | 2000 | BAM! Ent. |
| Nintendo Game Boy Color cart. | Dino Breeder 4 Model DMG-A4DJ-JPN | 2000 | J-Wing |
| Nintendo Game Boy Color cart. | Dinosaur Model CGB-BDNE-USA | 2000 | UBI Soft Ent., Inc. San Francisco, CA, USA 08888 |
| Nintendo Game Boy Color cart. | Dinosaur Model CGB-BDNP-EUR | 2000 | UBI Soft Creteil, France 307211 |
| Nintendo Game Boy Color cart. | Disney's 102 Dalmatians - Puppies to the Rescue Model CGB-B99E-USA | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Nintendo Game Boy Color cart. | Disney's 102 Dalmatians - Puppies to the Rescue Model CGB-B99P-UKV | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Nintendo Game Boy Color cart. | Disney's 102 Dalmatiner Model CGB-B99F-NOE | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Nintendo Game Boy Color cart. | Disney's Aladdin Model CGB-BADE-USA | 2000 | UBI Soft Ent., Inc. San Francisco, CA, USA 08888 |
| Nintendo Game Boy Color cart. | Disney's Aladdin Model CGB-BADP-EUR | 2000 | UBI Soft Creteil, France 307211 |
| Nintendo Game Boy Color cart. | Disney's Donald @#Duck?*! Model CGB-BQAE-USA | 2000 | UBI Soft Ent., Inc. San Francisco, CA, USA 08888 |
| Nintendo Game Boy Color cart. | Disney's Donald @#Duck?*! Model CGB-BQAP-EUR | 2000 | UBI Soft Creteil, France 307211 |
| Nintendo Game Boy Color cart. | Disney's Donald Duck - Daisy o Sukue! Model CGB-BUDJ-JPN | 2000 | UBI Soft Creteil, France 307211 |
| Nintendo Game Boy Color cart. | Disney's Doug - La Grande Aventure Model CGB-BDUF-FRA | 2000 | NewKidCo International, Inc. |
| Nintendo Game Boy Color cart. | Disney's Doug's Big Game Model CGB-BDUD-NOE | 2000 | NewKidCo International, Inc. |
| Nintendo Game Boy Color cart. | Disney's Doug's Big Game Model CGB-BDUE-USA | 2000 | NewKidCo International, Inc. |
| Nintendo Game Boy Color cart. | Disney's Doug's Big Game Model CGB-BDUP-EUR | 2000 | NewKidCo International, Inc. |
| Nintendo Game Boy Color cart. | Disney's Les 102 Dalmatiens à la Rescousse Model CGB-B99F-FRA | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
