| MSX cart. |  Young Sherlock - Doyle no Isan | 1985 | Pack-In-Video Co., Ltd. Japan |
| MSX cart. | Zanac A.I. Model R49X5093 | 1985 | Pony Canyon, Inc. Japan |
| MSX cart. | Zaxxon Model R48X5803 | 1985 | Pony Canyon, Inc. Japan |
| MSX cart. | Zexas Kousoku Limited Revolution Model MS1-G2109-P1 | 1985 | DB-SOFT Japan |
| MSX cart. | Zexas Kousoku Limited Revolution Model MS1-G2109-P2 | 1985 | DB-SOFT Japan |
| MSX cart. | 10-Yard Fight Model IM-02 P | 1986 | Irem Corp. Japan |
| MSX cart. | 123 Model P081 | 1986 | Al Alamiah |
| MSX cart. | 1942 Model 2019001 P | 1986 | ASCII Corp. Japan |
| MSX cart. | Add & Subtract Model M054 | 1986 | Al Alamiah |
| MSX cart. | Aladdin | 1986 | Barq |
| MSX cart. | Albatross | 1986 | Telenet Japan |
| MSX cart. | Aleph Ba Ta Model P078 | 1986 | Al Alamiah |
| MSX cart. | Alpha Roid Model R49X5103 | 1986 | Pony Canyon, Inc. Japan |
| MSX cart. | Aramo Model MXZS-11002 | 1986 | Sein Soft, Inc. Japan |
| MSX cart. | Arkanoid Model MSX-10 | 1986 | Taito Corp. Japan |
| MSX cart. | Around the Clock Model F048 | 1986 | Al Alamiah |
| MSX cart. | Attack Four - VolleyBall | 1986 | Pax Softonica Japan |
| MSX cart. | Back to the Future Model R49X5090 | 1986 | Pony Canyon, Inc. Japan |
| MSX cart. | Bank Panic Model R49X5807 P | 1986 | Pony Canyon, Inc. Japan |
| MSX cart. | Batten Tanuki no Daibouken Model MXTJ-11002 | 1986 | Tecno Soft. TechnoSoft Japan |
| MSX cart. | Bomber Man | 1986 | Korea Soft Bank |
| MSX cart. | Bouken Roman - Dota | 1986 | SystemSoft Corp. Japan |
| MSX cart. | Boullata Model G002 | 1986 | Al Alamiah |
| MSX cart. | Bull to Mighty Kiki Ippatsu Model HM-024 | 1986 | HAL Laboratory, Inc. Japan |
| MSX cart. | Burgertime | 1986 | Dempa Shinbunsha Japan |
| MSX cart. | Casio Worldopen | 1986 | Boram Soft. Korea |
| MSX cart. | Castle Excellent Model 2018109 | 1986 | ASCII Corp. Japan |
| MSX cart. | Champion Ice Hockey Model R49x5811 | 1986 | Pony Canyon, Inc. Japan |
| MSX cart. | Champion Kendo Model R49x5809 | 1986 | Pony Canyon, Inc. Japan |
| MSX cart. | Chou Senshi Zaider - Battle of Peguss | 1986 | Cosmos Computer Japan |
| MSX cart. | City Connection Model JX-10 P | 1986 | JALECO Co., Ltd. Japan |
| MSX cart. | Coaster Race Model HBS-G050C | 1986 | Sony Corp. Japan |
| MSX cart. | Come On! Picot Model R49X5100 | 1986 | Pony Canyon, Inc. Japan |
| MSX cart. | Cross Blaim Model MS1-G2113-L1 | 1986 | DB-SOFT Japan |
| MSX cart. | Dawn Patrol Model R49X5403 | 1986 | Pony Canyon, Inc. Japan |
| MSX cart. | Dragon Quest Model E-G186 | 1986 | Enix, Ltd. Japan |
| MSX cart. | Dungeon Master | 1986 | ASCII Corp. Japan |
| MSX cart. | Dunk Shot Model HM-021 | 1986 | HAL Laboratory, Inc. Japan |
| MSX cart. | El Gnomo Fedor en la Caverna Perdida | 1986 | Idealogic Barcelona, Spain |
| MSX cart. | Examine Your Information 2 Model E077 | 1986 | Al Alamiah |
