| Slot Machine |  Sapphire Sky | 2010 | Bally Tech., Inc. |
| Apple Store pack. | Saving Private Sheep | 2010 | Unknown |
| Microsoft XBOX 360 disc | SBK X - Superbike World Championship | 2010 | Black Bean Games |
| PC/MS-Windows CD | SBK X - Superbike World Championship | 2010 | Black Bean Games |
| Sony PlayStation 3 disc | SBK X - Superbike World Championship Model BLES-00774 | 2010 | Black Bean Games |
| Apple Store pack. | Scarface - The Last Stand | 2010 | Unknown |
| Apple Store pack. | Scarlett and the Spark of Life | 2010 | Unknown |
| Fruit Machine | Scoobie | 2010 | Empire Games, Ltd. Bridgend, England |
| Apple Store pack. | Score | 2010 | Unknown |
| Redemption mechanical game | Sea Wolf - The Next Mission | 2010 | Coastal Amusements, Inc. Lakewood, NJ, USA |
| Slot Machine | Secret Mine | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
| Apple Store pack. | Secret of Mana | 2010 | Unknown |
| Slot Machine | Secrets of the Forest | 2010 | IGT International Game Technologies Reno, NV, USA |
| GCE Vectrex | Sectis Hb | 2010 | Fury Unlimited |
| Arcade Video game | Sega Card-Gen MLB 2010 | 2010 | SEGA Corp. |
| Arcade Video game | Sega Golden Gun | 2010 | SEGA Corp. |
| PC/MS-Windows CD | Sega Mega Drive Classics Collection Vol. 1 | 2010 | SEGA Europe Ltd. |
| PC/MS-Windows CD | Sega Mega Drive Classics Collection Vol. 2 | 2010 | SEGA Europe Ltd. |
| PC/MS-Windows CD | Sega Mega Drive Classics Collection Vol. 3 | 2010 | SEGA Europe Ltd. |
| Sony PSN: Shodai PS Archives pack. |  Seiken Densetsu - Legend of Mana Model NPJI-????? | 2010 | Square Enix Co., Ltd. Japan |
| Sony PSN: Shodai PS Archives pack. | Sekai Saikyo Ginsei Igo 3 Model NPJI-????? | 2010 | Hamster Japan |
| Slot Machine | Sen Lin Wu Hui 2 Dai | 2010 | Richuang Technology Dev. Co., Ltd. Guangdong, China |
| Sony PlayStation 3 disc |  Sengoku Basara - Samurai Heroes Model BLES-00832 | 2010 | CE Europe, Ltd. Capcom Europe London, England 055060 |
| Sony PlayStation 3 disc | Sengoku Basara 3 Model BLJM-60218 | 2010 | Capcom Co., Ltd. Japan |
| Nintendo Wii disc | Sengoku Basara 3 Model RVL-SB3J-JPN | 2010 | Capcom Co., Ltd. Japan |
| Arcade Video game | Sengoku Taisen - 1560 Battle of Okehazama | 2010 | SEGA Corp. |
| Apple Store pack. | Sensible Soccer Skills | 2010 | Unknown |
| Sony PSN: Shodai PS Archives pack. | Sentimental Graffiti Model NPJI-????? | 2010 | GungHo Online Ent. |
| Apple Store pack. | Sentinel 3 - Homeworld | 2010 | Unknown |
| PC/MS-Windows pack. | Serious Sam HD - The Second Encounter | 2010 | GOG sp. z o.o. |
| PC/MS-Windows CD | Sexy Beach Zero | 2010 | Illusion Japan |
| Slot Machine | Sexy Mermaids | 2010 | Orion Gaming |
| Pachinko | Shabon Tama Holiday Pachinko Dayo Peanuts Model H4AX | 2010 | Heiwa Japan |
| Pachinko | Shabon Tama Holiday Pachinko Dayo Peanuts Model L1AW | 2010 | Heiwa Japan |
| Apple Store pack. | Shadow Guardian | 2010 | Unknown |
| Slot Machine | Shahrazad | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
| PC/MS-Windows DVD | Shaman's Sanctuary - Miko no Seiiki Model ALS-0071 18 | 2010 | Alicesoft Japan |
| PC/MS-Windows CD | Shamans Sanctuary - Miko no Seiki | 2010 | Alicesoft Japan |
| Slot Machine | Shambala | 2010 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Shaolin Legends | 2010 | WMS Gaming, Inc. Chicago, IL, USA |
