| Handheld game |  Space Rescue Model 60-2229 | 1990 | Radio Shack Fort Worth, TX, USA |
| Handheld game | Space Rescue Model MG-9 | 1982 | Tronica |
| Handheld game | Space Revenger Model SR-41V | 1983 | Tronica |
| Handheld game | Space Robot X25 | 1989 | Masudaya Corp. Japan |
| Handheld game | Space Scouts | 198? | Unknown Russia |
| Handheld game | Space Shield | 1989 | Masudaya Corp. Japan |
| Handheld game | Space Shoot | 198? | LIWACO Liebermann, Waelchli & Co |
| Handheld game | Space Shot Model 60-2166 | 1982 | Tandy Corp. |
| Handheld game | Space Shot Model 7934 | 1979 | Bandai Co., Ltd. Japan |
| Handheld game | Space Shuttle | 198? | POP Game |
| Handheld game | Space Shuttle 3 in 1 | 198? | Bandai Co., Ltd. Japan |
| Handheld game | Space Shuttle Model SS-03 | 198? | Men Star Electronics, Ltd. |
| Handheld game | Space Station Model 4979 | 1982 | Masudaya Corp. Japan |
| Handheld game | Space Trip Model 4975 | 198? | Masudaya Corp. Japan |
| Handheld game | Space War | 198? | Wizen |
| Handheld game | Space-N-Counter Model AC 1000 | 1980 | GCE General Consumer Electric |
| Handheld game | Spaceman | 199? | Systema |
| Handheld game | Spaceship Pinball Model 2373 | 1980 | Toytronic |
| Handheld game | Speak & Math | 1986 | Texas Instruments |
| Handheld game | Speak & Read | 1980 | Texas Instruments |
| Handheld game | Speak & Spell | 1978 | Texas Instruments |
| Handheld game | Speak & Spell Compact | 1981 | Texas Instruments |
| Handheld game | Speak & Write | 1982 | Texas Instruments |
| Handheld game | Speed Boat | 1991 | Tiger Electronic Toys, Inc. Orchard Mundelein, IL, USA |
| Handheld game | Speed Freak Model 5171 | 1982 | Mattel Electronics Mattel, Inc. |
| Handheld game | Speedway | 198? | Radio Shack Fort Worth, TX, USA |
| Handheld game | Spelling aBc | 1978 | Texas Instruments |
| Handheld game | Spider Model SG-21 | 1982 | Tronica |
| Handheld game | Spider-Man | 199? | Tiger Electronic Toys, Inc. Orchard Mundelein, IL, USA |
| Handheld game | Spider-Man 3 | 200? | Techno Source |
| Handheld game | Spider-Man Alt. model | 198? | Tiger Electronic Toys, Inc. Orchard Mundelein, IL, USA |
| Handheld game | Spitball Sparky Model BU-201 | 1984 | Nintendo Co., Ltd. Japan |
| Handheld game | Splatterhouse Model LCD-113 | 1988 | Varie Corp. Japan |
| Handheld game | Split Second | 1980 | Miro-Meccano France |
| Handheld game | Split Second Model 3700 | 1980 | Parker Bros. Beverly, MA, USA |
| Handheld game | Sport-Billy Football | 1986 | LIWACO Liebermann, Waelchli & Co |
| Handheld game | Sports Arena Model 60-2158 | 1981 | Tandy Corp. |
| Handheld game | Sports Center Model 2009 | 1980 | House of Games, Inc. Waddingtons Evanston, IL, USA |
| Handheld game | Sports Feel: Golf | 1998 | Tiger Electronic Toys, Inc. Orchard Mundelein, IL, USA |
| Handheld game | Squirrel & Monkey Model AG-28 | 1984 | Tronica |
