| Nintendo GBA cart. |  Ultimate Brain Games Model AGB-ABUE-USA | 2005 | Telegames, Inc. TX, USA |
| Nintendo GBA cart. | Ultimate Puzzle Games Model AGB-BUAE-USA | 2005 | Telegames, Inc. TX, USA |
| Nintendo GameCube disc | Ultimate Spider-Man | 2005 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| PC/MS-Windows CD | Ultimate Spider-Man | 2005 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Microsoft XBOX disc | Ultimate Spider-Man | 2005 | Unknown |
| Nintendo GBA cart. | Ultimate Spider-Man Model AGB-BULE-USA | 2005 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo GBA cart. | Ultimate Spider-Man Model AGB-BULP | 2005 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo DS cart. | Ultimate Spider-Man Model NTR-AUSE-USA | 2005 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| PC/MS-Windows CD | Ultra Mahou Shoujo Manana Vol.4 | 2005 | Alicesoft Japan |
| PC/MS-Windows CD | Ultra Mahou Shoujo Manana Vol.5 | 2005 | Alicesoft Japan |
| Pachislot | Ultraman Club ST | 2005 | Sammy Corp. Japan |
| Pachinko | Umi Densetsu | 2005 | Daiichi Denshi |
| Sega NAOMI GD-ROM | Under Defeat Model GDL-0035 | 2005 | G.Rev |
| Slot Machine | Unicorn Tales | 2005 | IGT International Game Technologies Reno, NV, USA |
| MSX cart. | Universe Unknown Hb | 2005 | Infinite |
| Microsoft XBOX disc | Unreal Championship 2 - The Liandri Conflict | 2005 | Unknown |
| Sony PSP UMD | Untold Legends - Brotherhood of the Blade Model ULUS-10003 | 2005 | Sony Online Ent., Inc. |
| Arcade Video game | Usagi Online | 2005 | Warashi, Inc. |
| PC/MS-Windows CD | Utopia City | 2005 | Reef Ent., Ltd. |
| Sony PlayStation CD |  Valkyrie Profile Model SLPM-87354 | 2005 | Square Enix Co., Ltd. Japan |
| Sony PlayStation 2 disc | Vampire - Darkstalkers Collection Model SLPM-65998 | 2005 | Capcom Co., Ltd. Japan |
| Medal video game | Very Good 2 | 2005 | Unknown Korea |
| Dedicated Console (based on NES) | VG Pocket | 2005 | Performance Designed Products |
| Pachislot | Victory 30-Pai Black model | 2005 | Bellco Corp. Japan |
| Pachislot | Victory 30-Pai Blue model | 2005 | Bellco Corp. Japan |
| Video Slot Machine | Video Risc | 2005 | Bally Wulff |
| Nintendo DS cart. | Viewtiful Joe - Double Trouble! Model NTR-AVJE-USA | 2005 | Capcom Ent., Inc. USA 13388 |
| Nintendo GameCube disc | Viewtiful Joe - Red Hot Rumble | 2005 | Capcom Ent., Inc. USA 13388 |
| Nintendo GameCube disc |  Viewtiful Joe - Red Hot Rumble Model DOL-GVCP-EUR | 2005 | CE Europe, Ltd. Capcom Europe London, England 055060 |
| Nintendo GameCube disc | Viewtiful Joe 2 Model DOL-G2VP-EUR | 2005 | CE Europe, Ltd. Capcom Europe London, England 055060 |
| Nintendo DS cart. | Viewtiful Joe: Scratch! Model NTR-AVJJ-JPN | 2005 | Capcom Co., Ltd. Japan |
| MSX cart. | Viking Hb | 2005 | Tur, José Luis |
| Sony PSP UMD | Virtua Tennis - World Tour | 2005 | SEGA of America, Inc. San Francisco, CA, USA |
| Microsoft XBOX disc | Virtual Pool - Tournament Edition | 2005 | Unknown |
| Medal video game | Vitamin | 2005 | Hannori Multimedia Content |
| Medal video game | Vitamin A | 2005 | Hannori Multimedia Content |
| Medal video game | Vitamin Plus | 2005 | Hannori Multimedia Content |
| PC/MS-Windows CD | Vivisector - Beast Within | 2005 | 1C Co. Russia |
| Arcade Video game |  VM Japan - Maboroshi Furan Senki | 2005 | Aruze Corp. Japan |
| Microsoft XBOX disc | Volvo - Drive For Life | 2005 | Unknown |
