| Sony PlayStation CD |  Shinseiden Megaseed Fukkatsu-Hen Model SLPS-00925 | 1997 | Banpresto Japan |
| Sega Saturn CD | Shinseiki Evangelion - 2nd Impression | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Shinsetsu Samurai Spirits - Bushidoh Retsuden | 1997 | SNK Corp. Shin Nihon Kikaku Japan |
| SNK Neo-Geo CD | Shinsetsu Samurai Spirits - Bushidoh Retsuden Model NGCD-0850 | 1997 | SNK Corp. Shin Nihon Kikaku Japan |
| Sony PlayStation CD | Shinsetsu Samurai Spirits - Bushidoh Retsuden Model SLPS-00814 | 1997 | SNK Corp. Shin Nihon Kikaku Japan |
| NEC PC-Engine CD | Shinsetsu Shiawase Usagi f - Yuujou Yori mo Aiyoku | 1997 | Unknown Japan |
| Sony PlayStation CD |  Shinshuku Taisen - It's a Nony! Taikenban Model SLPM-80156 | 1997 | TMF Japan |
| Sony PlayStation CD | Shinshuku Taisen - It's a Nony! Model SLPS-01114 | 1997 | TMF Japan |
| PC/MS-Windows CD | Shipwreckers! | 1997 | Psygnosis, Ltd. |
| Sony PlayStation CD | Shipwreckers! Demo Disc Model SLUS-90013 | 1997 | Psygnosis, Ltd. |
| Sony PlayStation CD | Shipwreckers! Model SLUS-00558 | 1997 | Psygnosis, Ltd. |
| Arcade Video game | Shiritsu Justice Gakuen - Legion of Heroes | 1997 | Capcom Co., Ltd. Japan |
| PC/MS-Windows CD | Shivers Two - Harvest of Souls | 1997 | Sierra Ent., Inc. USA |
| SNK Neo-Geo MVS cart. | Shock Troopers Model NGM-238 | 1997 | SNK Corp. Shin Nihon Kikaku Japan |
| Arcade Video game | Shocking | 1997 | Yun Sung Korea |
| MSX Turbo-R disk | Shoot That Flying Windows! (Fin) Hb | 1997 | Unknown |
| PC/MS-Windows CD | Shooting Tsukuru 95 | 1997 | ASCII Corp. Japan |
| Arcade Video game | Shootris | 1997 | HiCom Korea |
| MSX Turbo-R disk | Shoulder Blade Hb | 1997 | Unknown Japan |
| Redemption mechanical game | Shuffle Pool | 1997 | SEGA Pinball, Inc. Melrose Park, IL, USA |
| Arcade Video game | Shuffleshot | 1997 | Incredible Technologies, Inc. Rolling Meadows, IL, USA |
| Sony PlayStation CD | Shutokou Battle R - Highlight-ban Model SLPM-80088 | 1997 | Genki Co., Ltd. Japan |
| Sony PlayStation CD | Shutokou Battle R Model SLPS-00828 | 1997 | Genki Co., Ltd. Japan |
| Sega Saturn CD | Shutsudou! Mini-skirt Police | 1997 | Sada Soft Genki |
| NEC PC-9801 Series 5.25in. disk | Shuukan From H 18 | 1997 | Jast Japan |
| Sega Saturn CD | Sid Meier's Civilization - Shin Sekai Shichi Dai Bunmei Model T-2003G | 1997 | Asmik Co., Ltd. Japan |
| PC/MS-Windows CD | Sid Meier's Gettysburg | 1997 | Electronic Arts CA, USA 14633 |
| Slot Machine | Side Action 21 | 1997 | WMS Gaming, Inc. Chicago, IL, USA |
| Slot Machine | Side Bet 21 | 1997 | WMS Gaming, Inc. Chicago, IL, USA |
| Arcade Video game | Side By Side 2 | 1997 | Taito Corp. Japan |
| Sony PlayStation CD | Side by Side Special Demo Model SLPM-80145 | 1997 | Taito Corp. Japan |
| Sony PlayStation CD | Side by Side Special Model SLPS-01175 P | 1997 | Taito Corp. Japan |
| Sega Saturn CD | Side Pocket 3 | 1997 | Data East Corp. Japan |
| Sega Saturn CD | Side Pocket 3 Sample | 1997 | Data East Corp. Japan |
| Sony PlayStation CD | Sidewinder 2 Model SLPS-00954 | 1997 | Asmik Co., Ltd. Japan |
| Sega Saturn CD | Silhouette Mirage Taikan CD-ROM Sousa Setsumei Model 610-6679 | 1997 | ESP Ent. Soft. Publishing |
| Sega Saturn CD | Silhouette Mirage Model T-32901G | 1997 | ESP Ent. Soft. Publishing |
| Acorn Archimedes disk | Silver Ball | 1997 | Fourth Dimension, The |
| Nintendo 64 cart. |  SimCopter 64 | 1997 | Maxis Soft. Moraga, CA, USA |
| PC/MS-Windows CD | SimLife | 1997 | Electronic Arts CA, USA 14633 |
