| PC/MS-Windows pack. |  Inferno - Beyond the 7th Circle | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | InfraSpace | 2021 | GOG sp. z o.o. |
| Arcade Video game | Initial D The Arcade | 2021 | Konami Amusement Co., Ltd. Japan |
| PC/MS-Windows pack. | Inquisitor's Heart and Soul | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Inscryption | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. |  Inscryption Demo | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Inspector Waffles | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Inspector Waffles - Purrluxe Edition | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Insurmountable | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Insurmountable - Supporter Bundle | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | International Basketball Manager 22 Model 1461100 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Into the Pit | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Intravenous | 2021 | GOG sp. z o.o. |
| Sega Genesis cart. | Irena - Genesis Metal Fury demo | 2021 | White Ninja Studio |
| PC/MS-Windows pack. | Iron Commando Demo Model 1540820 | 2021 | Steam Valve Corp. |
| Sinclair ZX Spectrum cass. | Italia 1944 Hb | 2021 | Zankle Soft |
| PC/MS-Windows pack. | Jackpot Bennaction - B01, Discover The Mystery Combination Model 1702400 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B02, Discover The Mystery Combination Model 1747150 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B03, Discover The Mystery Combination Model 1748490 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B04, Discover The Mystery Combination Model 1760220 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B05, Discover The Mystery Combination Model 1761030 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B06, Discover The Mystery Combination Model 1761690 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B07, Discover The Mystery Combination Model 1761810 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B08, Discover The Mystery Combination Model 1762300 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B09, Discover The Mystery Combination Model 1762910 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B10, Discover The Mystery Combination Model 1762950 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B11, Discover The Mystery Combination Model 1763040 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B12, Discover The Mystery Combination Model 1765500 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B13, Discover The Mystery Combination Model 1765620 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Jackpot Bennaction - B14, Discover The Mystery Combination Model 1765630 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | JARS | 2021 | GOG sp. z o.o. |
| NEC TurboGrafx-CD | Jessie Jaeger in Cleopatra's Curse Hb | 2021 | Bold Game Studio |
| Arcade Video game | Jet Blaster | 2021 | SEGA Amusements, Inc. Elk Grove Village, IL, USA |
| PC/MS-Windows pack. | Jet Kave Adventure | 2021 | GOG sp. z o.o. |
| Pinball | John Carpenter’s Halloween | 2021 | Spooky Pinball, LLC |
| PC/MS-Windows pack. | Journey to the Savage Planet | 2021 | GOG sp. z o.o. |
| TRS-80 CoCo disk | Joust Hb | 2021 | Hewlett, Glen |
| PC/MS-Windows pack. | Jumpala | 2021 | GOG sp. z o.o. |
| Arcade Video game | Kasiori | 2021 | Success Japan |
| PC/MS-Windows pack. | Kathy Rain - Director's Cut | 2021 | GOG sp. z o.o. |
