| PC/MS-Windows pack. |  Mystery Case Files - 13th Skull Collector's Edition Model 514700 | 2016 | Steam Valve Corp. |
| PC/MS-Windows pack. | Mystery Case Files - Escape from Ravenhearst Model 438560 | 2016 | Steam Valve Corp. |
| PC/MS-Windows CD | Mystery Chronicle - One Way Heroics | 2016 | Spike Chunsoft Japan |
| Slot Machine | Mystery of the Congo | 2016 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Mythical Warriors - Centaurs | 2016 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Mythical Warriors - Mermaids | 2016 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Mythical Warriors - Sirenes | 2016 | IGT International Game Technologies Reno, NV, USA |
| Google Play pack. | Narcos - Cartel Wars | 2016 | FTX Games, Ltd. |
| Sony PlayStation 4 BR | Natural Doctrine Model PLJS-70001 | 2016 | Kadokawa Games, Ltd. Japan |
| Google Play pack. | NBA Live Mobile | 2016 | EA Sports |
| PC/MS-Windows pack. | Necropolis - Brutal Edition | 2016 | GOG sp. z o.o. |
| Arcade Video game |  Neon FM | 2016 | Andamiro Co., Ltd. |
| Nintendo NES cart. | NES Virus Cleaner Hb | 2016 | Second Dimension |
| PC/MS-Windows pack. | NeuroVoider Model 400450 | 2016 | Steam Valve Corp. |
| PC/MS-Windows pack. | Nevertales - The Beauty Within Collector's Edition Model 466010 | 2016 | Steam Valve Corp. |
| Online Slot | Night Club 81 | 2016 | Wazdan |
| Slot Machine | Night Witch | 2016 | Incredible Technologies, Inc. Rolling Meadows, IL, USA |
| Apple tvOS pack. | Nightgate | 2016 | Unknown |
| Pachislot | Ninja Gaiden | 2016 | Nanashow Japan |
| Dedicated Console | Nintendo Entertainment System Classic Edition | 2016 | Nintendo of America, Inc. USA 45496 |
| PC/MS-Windows pack. | No Man's Sky | 2016 | GOG sp. z o.o. |
| MSX 2 cart. | No Ren-Sha Hb | 2016 | Ochixn |
| Sony PlayStation 3 disc | Nobunaga no Yabou Souzou - Sengoku Risshiden Model BLJM-61333 | 2016 | KOEI Tecmo Games Co., Ltd. Japan |
| PC/MS-Windows pack. | Nobunaga's Ambition - Sphere of Influence - Ascension Model 375450 | 2016 | Steam Valve Corp. |
| PC/MS-Windows pack. | Nobunaga's Ambition Model 544990 | 2016 | Steam Valve Corp. |
| PC/MS-Windows pack. | Noctropolis | 2016 | GOG sp. z o.o. |
| Apple tvOS pack. | Nodes of Yesod - 30th Anniversary Edition | 2016 | Unknown |
| Google Play pack. | Nonogram King | 2016 | Mobirix |
| Google Play pack. | Nonstop Knight | 2016 | Flaregames |
| PC/MS-Windows CD | O Tanoshimi CD 124 | 2016 | WestSide Japan |
| PC/MS-Windows pack. | Obduction | 2016 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Obscuritas | 2016 | GOG sp. z o.o. |
| Pachinko | Oda Nobuna no Yabou | 2016 | Nishijin Japan |
| PC/MS-Windows pack. | Oddworld - Munch's Oddysee | 2016 | GOG sp. z o.o. |
| Sony PlayStation 3 disc | Odin Sphere Leifdrasir Model BLJM-61239 | 2016 | Atlus Co., Ltd. Japan |
| PC/MS-Windows pack. | Of Light and Darkness - The Prophecy | 2016 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Offworld Trading Company | 2016 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Oh...Sir!! The Insult Simulator | 2016 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Okhlos - Omega | 2016 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Okhlos - Omega - Olympus Edition | 2016 | GOG sp. z o.o. |
