| Arcade Video game |  DrumMania XG | 2010 | Konami Digital Ent. Co., Ltd. |
| Redemption mechanical game | Ducky Splash | 2010 | UNIS Universal Space Ontario, Canada |
| Sony PlayStation 3 disc | Dynasty Warriors - Strikeforce Model BLUS-30471 | 2010 | KOEI Co., Ltd. Japan |
| Nintendo Wii disc |  EA Best Hits: Tiger Woods PGA Tour 09 - All-Play Model RVL-R9TJ-JPN-1 | 2010 | EA Sports |
| Nintendo Wii disc | EA Sports Active - NFL Training Camp Model RVL-SNFE-USA | 2010 | EA Sports |
| Nintendo Wii disc | EA Sports Active - Personal Trainer Wii - 6-shuukan Shuuchuu Hikishime Program Model RVL-SEAJ-JPN | 2010 | EA Sports |
| Sony PlayStation 3 disc | EA Sports Active 2 | 2010 | EA Sports |
| Microsoft XBOX 360 disc | EA Sports Active 2 | 2010 | EA Sports |
| Nintendo Wii disc | EA Sports Active 2 Model RVL-SE2E-USA | 2010 | EA Sports |
| Nintendo Wii disc | EA Sports Active 2 Model RVL-SE2P-EUR | 2010 | EA Sports |
| Slot Machine | Eastern Charm | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
| Sony PlayStation 3 disc | Eat Lead - Matt Hazard no Gyakushuu Model BLJS-10076 | 2010 | D3 Publisher, Inc. |
| Sony PSP UMD | Echoshift | 2010 | Sony Computer Ent. Europe SCEE |
| Slot Machine | Egyptian Mysteries | 2010 | Magic Dreams |
| Slot Machine | Egyptian Sunset | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
| Sony PSN: Shodai PS Archives pack. |  Elan Plus Model NPJI-????? | 2010 | Hamster Japan |
| Sony PSN: Shodai PS Archives pack. | Elan Model NPJI-????? | 2010 | Hamster Japan |
| Slot Machine | Electrifying Riches | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
| Acorn Electron 5.25in. disk | Electron User Group #70 | 2010 | EUG Electron User Group |
| Acorn Electron 5.25in. disk | Electron User Group #71 | 2010 | EUG Electron User Group |
| Acorn Electron 5.25in. disk | Electron User Group #72 | 2010 | EUG Electron User Group |
| Acorn Electron 5.25in. disk | Electron User Group #73 | 2010 | EUG Electron User Group |
| PC/MS-Windows DVD | Elemental - War of Magic | 2010 | Stardock Ent. |
| Slot Machine | Elfy | 2010 | EVG spa Elettronica Video-Games Cormano, MI, Italy |
| Fruit Machine | Elvis Smash Hits Party Cat. B2 | 2010 | Barcrest Games |
| Fruit Machine | Elvis Smash Hits Party Cat. B3 | 2010 | Barcrest Games |
| Fruit Machine | Elvis Top 20 Cat. B2 | 2010 | Barcrest Games |
| Slot Machine | Emerald Treasures Mega Series | 2010 | Bally Tech., Inc. |
| PC/MS-Windows CD | Emergency 2012 | 2010 | Deep Silver, Inc. |
| Slot Machine | Emperor's Sword | 2010 | Bally Tech., Inc. |
| Slot Machine | Empire | 2010 | AC Coin & Slot USA |
| PC/MS-Windows pack. | Empire Earth 2 - Gold Edition | 2010 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Empire Earth 3 | 2010 | GOG sp. z o.o. |
| Arcade Video game | En-Eins Perfektewelt | 2010 | Subtle Style |
| Slot Machine | Enchanted World Double Hit Game Plus | 2010 | Ainsworth Game Technology, Ltd. |
| PC/MS-Windows pack. | Enclave | 2010 | GOG sp. z o.o. |
| Microsoft XBOX 360 disc | Enslaved - Odyssey to the West | 2010 | NAMCO Bandai Games, Inc. Japan |
| Sony PlayStation 3 disc | Enslaved - Odyssey to the West Model BLJS-10089 | 2010 | NAMCO Bandai Games, Inc. Japan |
| Sony PlayStation 3 disc | Enslaved - Odyssey to the West Model BLUS-30558 | 2010 | NAMCO Bandai Games America, Inc. |
| Pachinko | Enter the Matrix | 2010 | Daiichi Denshi |
